methyl 2,3,4-tri-O-benzyl-4-C-methyl-6-O-triphenylmethyl-α-D-glucopyranoside

Base Information

• Chemical Name: methyl 2,3,4-tri-O-benzyl-4-C-methyl-6-O-triphenylmethyl-α-D-glucopyranoside
• CAS No.: 160835-79-0
• Molecular Formula: C₄₈H₄₈O₆
• Molecular Weight: 720.906
• Mol file: 160835-79-0.mol

Synonyms:methyl 2,3,4-tri-O-benzyl-4-C-methyl-6-O-triphenylmethyl-α-D-glucopyranoside

Chemical Property of methyl 2,3,4-tri-O-benzyl-4-C-methyl-6-O-triphenylmethyl-α-D-glucopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 2,3,4-tri-O-benzyl-4-C-methyl-6-O-triphenylmethyl-α-D-glucopyranoside

There total 2 articles about methyl 2,3,4-tri-O-benzyl-4-C-methyl-6-O-triphenylmethyl-α-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl 2,3-di-O-benzyl-6-O-triphenylmethyl-α-D-xylo-hexopyranosid-4-ulose (81255-12-1) → methyl 2,3,4-tri-O-benzyl-4-C-methyl-6-O-triphenylmethyl-α-D-glucopyranoside (160835-79-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 72 percent / diethyl ether / -78 °C

2: 1.) NaH / 1.) DMF, RT, 30 min, 2.) DMF

With sodium hydride; In diethyl ether;

DOI:10.1246/bcsj.67.1633

Reference yield:

benzyl bromide (100-39-0) + methyl 2,3-di-O-benzyl-4-C-methyl-6-O-triphenylmethyl-α-D-glucopyranoside (81255-13-2) → methyl 2,3,4-tri-O-benzyl-4-C-methyl-6-O-triphenylmethyl-α-D-glucopyranoside (160835-79-0)

Guidance literature:

With sodium hydride; Yield given. Multistep reaction; 1.) DMF, RT, 30 min, 2.) DMF;

DOI:10.1246/bcsj.67.1633

Reference yield: 100.0%

methyl 2,3,4-tri-O-benzyl-4-C-methyl-6-O-triphenylmethyl-α-D-glucopyranoside (160835-79-0) → methyl 2,3,4-tri-O-benzyl-4-C-methyl-α-D-glucopyranoside (160835-80-3)

Guidance literature:

With acetic acid; at 60 ℃;

DOI:10.1246/bcsj.67.1633

upstream raw materials:

benzyl bromide

methyl 2,3-di-O-benzyl-4-C-methyl-6-O-triphenylmethyl-α-D-glucopyranoside

methyl 2,3-di-O-benzyl-6-O-triphenylmethyl-α-D-xylo-hexopyranosid-4-ulose

Downstream raw materials:

methyl 2,3,4-tri-O-benzyl-4-C-methyl-α-D-glucopyranoside

methyl 2,3,4-tri-O-benzyl-6-deoxy-4-C-methyl-α-D-xylo-hex-5-enopyranoside

methyl 2,3,4-tri-O-benzyl-4-C-methyl-6-O-(p-tolylsulfonyl)-α-D-glucopyranoside