methyl 1-chloro-4-hydroxy-7-phenoxyisoquinoline-3-carboxylate

Base Information

Chemical Name:methyl 1-chloro-4-hydroxy-7-phenoxyisoquinoline-3-carboxylate
CAS No.:1421312-35-7
Molecular Formula:C₁₇H₁₃NO₄
Molecular Weight:295.295
Hs Code.:
Mol file:1421312-35-7.mol

Synonyms:4-hydroxy-1-methyl-7-phenoxy-3-isoquinolinecarboxylic acid

Suppliers and Price of methyl 1-chloro-4-hydroxy-7-phenoxyisoquinoline-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 28 raw suppliers

Chemical Property of methyl 1-chloro-4-hydroxy-7-phenoxyisoquinoline-3-carboxylate

Chemical Property:

Boiling Point:552.7±50.0 °C(Predicted)
PKA:0.10±0.30(Predicted)
Density:1.376±0.06 g/cm3(Predicted)

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 1-chloro-4-hydroxy-7-phenoxyisoquinoline-3-carboxylate

There total 52 articles about methyl 1-chloro-4-hydroxy-7-phenoxyisoquinoline-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 4-hydroxy-1-methyl-7-phenoxy-3-isoquinoline ethyl carboxylate

: 1421312-35-7
4-hydroxy-1-methyl-7-phenoxy-3-isoquinolinecarboxylic acid

Guidance literature:: 4-hydroxy-1-methyl-7-phenoxy-3-isoquinoline ethyl carboxylate; With sodium hydroxide; In ethanol; at 80 ℃;

With hydrogenchloride; In ethanol; water;
DOI:10.1021/acs.oprd.1c00281

Reference yield: 95.4%

: methyl 4-hydroxy-1-iodo-7-phenoxyisoquinoline-3-carboxylate

: 1421312-35-7
4-hydroxy-1-methyl-7-phenoxy-3-isoquinolinecarboxylic acid

Guidance literature:: methyl 4-hydroxy-1-iodo-7-phenoxyisoquinoline-3-carboxylate; isopropyl methyl borate; With bis-triphenylphosphine-palladium(II) chloride; potassium carbonate; In 2-methoxy-ethanol; water; at 90 - 100 ℃; for 4h;

With hydrogenchloride; In water; at 20 - 30 ℃; pH=2-3;