(3R,5R)-5-(4-(4-chlorobenzyl)-5-methyl-4H-1,2,4-triazol-3-yl)pyrrolidin-3-yl acetate hydrochloride

Base Information

Chemical Name:(3R,5R)-5-(4-(4-chlorobenzyl)-5-methyl-4H-1,2,4-triazol-3-yl)pyrrolidin-3-yl acetate hydrochloride
CAS No.:1140496-23-6
Molecular Formula:C₁₆H₁₉ClN₄O₂*ClH
Molecular Weight:371.266
Hs Code.:

Synonyms:(3R,5R)-5-(4-(4-chlorobenzyl)-5-methyl-4H-1,2,4-triazol-3-yl)pyrrolidin-3-yl acetate hydrochloride

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Chemical Property of (3R,5R)-5-(4-(4-chlorobenzyl)-5-methyl-4H-1,2,4-triazol-3-yl)pyrrolidin-3-yl acetate hydrochloride

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Technology Process of (3R,5R)-5-(4-(4-chlorobenzyl)-5-methyl-4H-1,2,4-triazol-3-yl)pyrrolidin-3-yl acetate hydrochloride

There total 1 articles about (3R,5R)-5-(4-(4-chlorobenzyl)-5-methyl-4H-1,2,4-triazol-3-yl)pyrrolidin-3-yl acetate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1140496-22-5
(2R,4R)-tert-butyl-2-(4-(4-chlorobenzyl)-5-methyl-4H-1,2,4-triazol-3-yl)-4-acetoxypyrrolidine-1-carboxylate

: 1140496-23-6
(3R,5R)-5-(4-(4-chlorobenzyl)-5-methyl-4H-1,2,4-triazol-3-yl)pyrrolidin-3-yl acetate hydrochloride

Guidance literature:: With hydrogenchloride; ethanol; at 20 ℃; for 2h;

Reference yield: 100.0%

: 32315-10-9
bis(trichloromethyl) carbonate

: 1140496-05-4
(S)-7-(trifluoromethyl)chroman-4-amine

: 1140496-23-6
(3R,5R)-5-(4-(4-chlorobenzyl)-5-methyl-4H-1,2,4-triazol-3-yl)pyrrolidin-3-yl acetate hydrochloride

: 1140496-24-7
(3R,5R)-1-(((S)-7-(trifluoromethyl)chroman-4-yl)carbamoyl)-5-(4-(4-chlorobenzyl)-5-methyl-4H-1,2,4-triazol-3-yl)pyrrolidin-3-yl acetate

Guidance literature:: bis(trichloromethyl) carbonate; (S)-7-(trifluoromethyl)chroman-4-amine; With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 0.25h;

(3R,5R)-5-(4-(4-chlorobenzyl)-5-methyl-4H-1,2,4-triazol-3-yl)pyrrolidin-3-yl acetate hydrochloride; In dichloromethane; at 20 ℃; for 16h;