[5-(4-fluoro-2-hydroxyphenyl)-3-(4-methoxyphenyl)-1H-pyrrol-2-yl]-[5-(4-fluoro-2-hydroxyphenyl)-3-(4-methoxyphenyl)-pyrrol-2-ylidene]amine

Base Information

• Chemical Name: [5-(4-fluoro-2-hydroxyphenyl)-3-(4-methoxyphenyl)-1H-pyrrol-2-yl]-[5-(4-fluoro-2-hydroxyphenyl)-3-(4-methoxyphenyl)-pyrrol-2-ylidene]amine
• CAS No.: 1222171-44-9
• Molecular Formula: C₃₄H₂₅F₂N₃O₄
• Molecular Weight: 577.587
• Mol file: 1222171-44-9.mol

Synonyms:[5-(4-fluoro-2-hydroxyphenyl)-3-(4-methoxyphenyl)-1H-pyrrol-2-yl]-[5-(4-fluoro-2-hydroxyphenyl)-3-(4-methoxyphenyl)-pyrrol-2-ylidene]amine

Chemical Property of [5-(4-fluoro-2-hydroxyphenyl)-3-(4-methoxyphenyl)-1H-pyrrol-2-yl]-[5-(4-fluoro-2-hydroxyphenyl)-3-(4-methoxyphenyl)-pyrrol-2-ylidene]amine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [5-(4-fluoro-2-hydroxyphenyl)-3-(4-methoxyphenyl)-1H-pyrrol-2-yl]-[5-(4-fluoro-2-hydroxyphenyl)-3-(4-methoxyphenyl)-pyrrol-2-ylidene]amine

There total 1 articles about [5-(4-fluoro-2-hydroxyphenyl)-3-(4-methoxyphenyl)-1H-pyrrol-2-yl]-[5-(4-fluoro-2-hydroxyphenyl)-3-(4-methoxyphenyl)-pyrrol-2-ylidene]amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 27.0%

1-(4-fluoro-2-hydroxyphenyl)-3-(4-methoxyphenyl)-4-nitrobutan-1-one (1222171-43-8) → [5-(4-fluoro-2-hydroxyphenyl)-3-(4-methoxyphenyl)-1H-pyrrol-2-yl]-[5-(4-fluoro-2-hydroxyphenyl)-3-(4-methoxyphenyl)-pyrrol-2-ylidene]amine (1222171-44-9)

Guidance literature:

With ammonium acetate; acetic acid; at 110 ℃; for 5h;

DOI:10.1080/00397910903219542

Reference yield: 63.0%

[5-(4-fluoro-2-hydroxyphenyl)-3-(4-methoxyphenyl)-1H-pyrrol-2-yl]-[5-(4-fluoro-2-hydroxyphenyl)-3-(4-methoxyphenyl)-pyrrol-2-ylidene]amine (1222171-44-9) → C34H22BF2N3O4 (1245905-02-5)

Guidance literature:

With boron trifluoride diethyl etherate; N-ethyl-N,N-diisopropylamine; In toluene; for 1h; Reflux;

DOI:10.1080/00397910903219542

Reference yield: 61.0%

pyrrolidine (123-75-1) + [5-(4-fluoro-2-hydroxyphenyl)-3-(4-methoxyphenyl)-1H-pyrrol-2-yl]-[5-(4-fluoro-2-hydroxyphenyl)-3-(4-methoxyphenyl)-pyrrol-2-ylidene]amine (1222171-44-9) → C38H30BFN4O4 (1245905-03-6)

Guidance literature:

With boron trifluoride diethyl etherate; In toluene; at 110 ℃; for 1.5h;

DOI:10.1080/00397910903219542

upstream raw materials:

1-(4-fluoro-2-hydroxyphenyl)-3-(4-methoxyphenyl)-4-nitrobutan-1-one

Downstream raw materials:

C₃₈H₃₀BFN₄O₄

C₃₄H₂₂BF₂N₃O₄