Technology Process of (1H)-2-thioxo-1-pyridyl 9,9-diphenyl-3-methanesulfonyloxy-2-methoxy-2-methyl-8-nonenoate
There total 6 articles about (1H)-2-thioxo-1-pyridyl 9,9-diphenyl-3-methanesulfonyloxy-2-methoxy-2-methyl-8-nonenoate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
triethylamine;
In
dichloromethane;
at 0 - 20 ℃;
DOI:10.1021/ol034061o
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: 84 percent / LiAlH4 / diethyl ether / 2 h / 0 °C
2.1: 64 percent / pyridinium chlorochromate / CH2Cl2 / 3 h / 20 °C
3.1: lithium diisopropylamide / tetrahydrofuran; hexane / 1 h / -78 °C
3.2: 91 percent / tetrahydrofuran; hexane / 2 h
4.1: 100 percent / triethylamine / CH2Cl2 / 1 h / 0 °C
5.1: 85 percent / 2,2,2-trifluoroacetic acid / CH2Cl2
6.1: 80 percent / triethylamine / CH2Cl2 / 0 - 20 °C
With
lithium aluminium tetrahydride; triethylamine; pyridinium chlorochromate; trifluoroacetic acid; lithium diisopropyl amide;
In
tetrahydrofuran; diethyl ether; hexane; dichloromethane;
DOI:10.1021/ol034061o
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: lithium diisopropylamide / tetrahydrofuran; hexane / 1 h / -78 °C
1.2: 91 percent / tetrahydrofuran; hexane / 2 h
2.1: 100 percent / triethylamine / CH2Cl2 / 1 h / 0 °C
3.1: 85 percent / 2,2,2-trifluoroacetic acid / CH2Cl2
4.1: 80 percent / triethylamine / CH2Cl2 / 0 - 20 °C
With
triethylamine; trifluoroacetic acid; lithium diisopropyl amide;
In
tetrahydrofuran; hexane; dichloromethane;
DOI:10.1021/ol034061o
![2-oxo-[1,4,2]oxathiazolo[2,3-a]pyridin-4-ium chloride](/Databaselist/images/loading.webp)
