p-chlorophenyl α-fluoropropargyl sulfide

Base Information

• Chemical Name: p-chlorophenyl α-fluoropropargyl sulfide
• CAS No.: 349146-78-7
• Molecular Formula: C₉H₆ClFS
• Molecular Weight: 200.664
• Mol file: 349146-78-7.mol

Synonyms:p-chlorophenyl α-fluoropropargyl sulfide

Chemical Property of p-chlorophenyl α-fluoropropargyl sulfide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of p-chlorophenyl α-fluoropropargyl sulfide

There total 1 articles about p-chlorophenyl α-fluoropropargyl sulfide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

(4-chlorophenyl)(prop-2-yn-1-yl)sulfane (17277-23-5) → p-chlorophenyl α-fluoropropargyl sulfide (349146-78-7) + p-chlorophenyl α,α-difluoropropargyl sulfide

Guidance literature:

With triethylamine tris(hydrogen fluoride); In 1,2-dimethoxyethane; at 20 ℃; Electrolysis;

DOI:10.1016/S0040-4039(01)00344-6

Reference yield: 55.0%

p-chlorophenyl α-fluoropropargyl sulfide (349146-78-7) → p-chlorophenyl α-fluoroallenyl sulfide (349146-83-4)

Guidance literature:

With sodium ethanolate; In ethanol; at 20 ℃; for 3h;

DOI:10.1016/S0040-4020(02)00559-8

Reference yield:

p-chlorophenyl α-fluoropropargyl sulfide (349146-78-7) → p-chlorophenyl α-fluoroacetonyl sulfide

Guidance literature:

Multi-step reaction with 2 steps

1: 55 percent / sodium ethoxide / ethanol / 3 h / 20 °C

2: 65 percent / benzylamine; H₂O / tetrahydrofuran / 40 h / 20 °C

With water; sodium ethanolate; benzylamine; In tetrahydrofuran; ethanol;

DOI:10.1016/S0040-4020(02)00559-8

upstream raw materials:

(4-chlorophenyl)(prop-2-yn-1-yl)sulfane

Downstream raw materials:

p-chlorophenyl α-fluoroallenyl sulfide