O-ethyl S-4-oxo-4-phenyl-1-phthalimidomethylbutyl dithiocarbonate

Base Information

• Chemical Name: O-ethyl S-4-oxo-4-phenyl-1-phthalimidomethylbutyl dithiocarbonate
• CAS No.: 226920-42-9
• Molecular Formula: C₂₂H₂₁NO₄S₂
• Molecular Weight: 427.545
• Mol file: 226920-42-9.mol

Synonyms:O-ethyl S-4-oxo-4-phenyl-1-phthalimidomethylbutyl dithiocarbonate

Chemical Property of O-ethyl S-4-oxo-4-phenyl-1-phthalimidomethylbutyl dithiocarbonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of O-ethyl S-4-oxo-4-phenyl-1-phthalimidomethylbutyl dithiocarbonate

There total 2 articles about O-ethyl S-4-oxo-4-phenyl-1-phthalimidomethylbutyl dithiocarbonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

3-phthalimido-1-propene (5428-09-1) + O-ethyl S-[2-oxo-2-phenylethyl]carbonodithioate (56817-84-6) → O-ethyl S-4-oxo-4-phenyl-1-phthalimidomethylbutyl dithiocarbonate (226920-42-9)

Guidance literature:

With dilauryl peroxide; In 1,2-dichloro-ethane; for 7h; Reflux;

DOI:10.1016/j.tet.2012.10.029

Reference yield:

phthalic anhydride (85-44-9) → O-ethyl S-4-oxo-4-phenyl-1-phthalimidomethylbutyl dithiocarbonate (226920-42-9)

Guidance literature:

Multi-step reaction with 2 steps

1: acetic acid / 2 h / Reflux

2: dilauryl peroxide / 1,2-dichloro-ethane / 7 h / Reflux

With dilauryl peroxide; acetic acid; In 1,2-dichloro-ethane;

DOI:10.1016/j.tet.2012.10.029

Reference yield: 92.0%

O-ethyl S-4-oxo-4-phenyl-1-phthalimidomethylbutyl dithiocarbonate (226920-42-9) → 5-oxo-5-phenyl-1-phthalimidopentane-2-sulfonyl chloride (1454845-13-6)

Guidance literature:

With hydrogenchloride; N-chloro-succinimide; In water; acetonitrile; at 0 ℃; for 0.25h;

DOI:10.1016/j.tet.2013.08.028

upstream raw materials:

3-phthalimido-1-propene

O-ethyl S-[2-oxo-2-phenylethyl]carbonodithioate

phthalic anhydride

Downstream raw materials:

2-(5-oxo-5-phenylpentyl)isoindole-1,3-dione

2-phenyl-3,4,5,6-tetrahydropyridine

2-phenylpiperidine

1-benzoyl-2-phenylpiperidine