10.1016/j.tetlet.2014.09.103
The study presents an efficient and environmentally friendly one-pot synthesis method for benzo[a]phenazines and naphtho[2,3-d]imidazoles, which are important due to their biological properties such as antibiotic, antimalarial, antiparasitic, and antitumor activities. The synthesis was achieved using 2,3-dichloro-1,4-naphthoquinone as the starting material, o-phenylenediamine and benzamidines as nucleophiles, and sodium dodecyl sulfate (SDS) micelles as a catalyst in water. The purpose of these chemicals was to undergo nucleophilic substitution reactions, leading to the formation of the desired benzo[a]phenazine and naphtho[2,3-d]imidazole derivatives with excellent yields, demonstrating a green and regio- and chemoselective approach to synthesizing these potentially pharmaceutically significant compounds.
10.1039/c8nj00410b
The research focuses on the development and investigation of the catalytic activity of copper nanoparticles (CuNPs) supported on a Zinc oxide-polythiophene (ZnO-PTh) nanocomposite, denoted as CuNPs@ZnO-PTh. The purpose of this study was to create an efficient, cost-effective, and environmentally benign catalyst for the synthesis of propargylamine, tetra-substituted propargylamine, and pyrrolo[1,2-a]quinolines through A3 and KA2 coupling reactions. The researchers used a variety of chemicals in the synthesis process, including zinc chloride, sodium hydroxide, sodium dodecyl sulfate, thiophene, ferric chloride, copper nitrate trihydrate, and hydrazine hydrate. The conclusions drawn from the study highlight the high catalytic performance of the CuNPs@ZnO-PTh catalyst, which was attributed to its high surface area and the synergistic effect of both CuNPs and ZnO-PTh. The catalyst demonstrated excellent activity, selectivity, and recyclability, with the reactions yielding high product yields (up to 98%) in ethylene glycol, a green and biodegradable solvent, under microwave irradiation. The study concludes that this protocol is more efficient and sustainable compared to existing commercial methods.
10.1016/j.cclet.2018.04.017
The study focuses on the synthesis and evaluation of three novel fluorinated cationic surfactants derived from hexafluoropropylene dimer. These surfactants, characterized by branched short fluorinated tails and ammonium oxide polar groups, were found to possess excellent surface properties, reducing the surface tension of water to below 20.00 mN/m at their critical micelle concentrations (CMC). The study also explored the surfactants' compatibility when mixed with other types of surfactants, such as SDS, AOS, APG, and LAB, which are commonly used in fire-fighting foams. The combination of these novel fluorinated surfactants with hydrocarbon surfactants resulted in even lower CMC and surface tension values, suggesting their potential as sustainable alternatives to perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) in the formulation of aqueous film-forming foams (AFFFs) for firefighting applications. The research was supported by the National Natural Science Foundation of China and the Science and Technology Commission of Shanghai Municipality.
10.1007/s11172-007-0172-3
The research focuses on the synthesis and antioxidant properties of sodium S-[3-(hydroxyaryl)propyl] thiosulfates and [3-(hydroxyaryl)propane]-1-sulfonates, which are derivatives of spatially hindered phenols. These compounds were synthesized from dialkylphenols through a series of intermediate products, with the aim of creating hydrophilic "hybrid" compounds capable of inhibiting lipid peroxidation in various ways, thus serving as potential antioxidants for biological and medical applications. The experiments involved the oxidation of methyl oleate in aqueous sodium dodecyl sulfate (SDS), where the rate constants of the interaction of the synthesized compounds with lipoperoxide radicals were determined. This model reaction served as a satisfactory model for the oxidation of lipids in biomembranes. The analysis included the determination of the reactivity of the synthesized compounds towards peroxy radicals, which was quantified by the k3/k1 parameter, and was based on the experimentally determined values of the uninhibited oxidation rate (W0) and the inhibited oxidation rate (W). The study also involved the synthesis of various intermediates and final products, which were confirmed by elemental analysis and spectral data, including 1H NMR spectral data. The research was financially supported by the Russian Foundation for Basic Research.
10.2174/157017809787582717
The research presents a one-pot synthesis of 2-substituted imidazo[2,1-b][1,3]benzothiazoles via a Pd-Cu catalyzed coupling-cyclization reaction in water. The key chemicals involved include 2-imino-3-(2-propynyl)-1,3-benzothiazole as the starting material, various aryl iodides as coupling partners, bis(triphenylphosphine)palladium(II) chloride and copper iodide as catalysts, sodium lauryl sulfate as a surfactant, and potassium carbonate as a base. The reaction is performed in degassed water at 60 °C under an argon atmosphere, yielding 2-substituted imidazo[2,1-b][1,3]benzothiazoles in moderate to high yields. The study also explores the optimization of reaction conditions, such as the effects of different bases, catalyst amounts, and surfactant concentrations on the yield and efficiency of the reaction.
10.1039/P29900001105
The study investigates the light-triggered complexation of dioxygen by Co(II)-meso-tetraphenylporphyrin (Co"TPP) and its long-chain derivatives in aqueous micellar solutions. The researchers used Triton X-100, sodium dodecyl sulfate (SDS), and cetyltrimethylammonium bromide (CTAB) as the micelles. The study found that the complexation of dioxygen is induced by irradiation in the Soret band or the visible absorption band, and it is reversible at room temperature even in dilute detergent solutions. The initial binding of an ether oxygen of Triton or a water molecule to the cobalt atom is proposed as the first step, with visible irradiation ejecting one of these ligands to allow dioxygen to bind. The stability and reversibility of these systems are shown to be highly sensitive to the structure and environment of the metalloporphyrins, with the liquid interface playing a crucial role. The study provides quantum yields for the photo-processes and thermodynamic data for ionic and non-ionic micellar solutions, suggesting that these simple models can meet most conditions required for cobalt-reconstituted biological dioxygen carriers to function similarly to natural carriers.
Xi,
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F:Flammable;
