C₁₂H₁₂ClF₃O₃

Base Information

Chemical Name:C₁₂H₁₂ClF₃O₃
CAS No.:1541198-33-7
Molecular Formula:C₁₂H₁₂ClF₃O₃
Molecular Weight:296.674
Hs Code.:

C<sub>12</sub>H<sub>12</sub>ClF<sub>3</sub>O<sub>3</sub>

Synonyms:C₁₂H₁₂ClF₃O₃

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Chemical Property of C₁₂H₁₂ClF₃O₃

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Technology Process of C₁₂H₁₂ClF₃O₃

There total 2 articles about C₁₂H₁₂ClF₃O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 14862-52-3
1,3-dibromo-5-chlorobenzene

: 1541198-33-7
C₁₂H₁₂ClF₃O₃

Guidance literature:: Multi-step reaction with 3 steps

1.1: n-butyllithium / hexane; di-isopropyl ether / 0.5 h / -78 °C / Inert atmosphere

1.2: -78 °C / Inert atmosphere

2.1: toluene-4-sulfonic acid / toluene / 6 h / Reflux; Dean-Stark

3.1: tert.-butyl lithium / hexane; di-isopropyl ether / 0.5 h / -78 °C / Inert atmosphere

3.2: 0.5 h / -30 °C / Inert atmosphere

With n-butyllithium; tert.-butyl lithium; toluene-4-sulfonic acid; In hexane; di-isopropyl ether; toluene;

Reference yield:

: 188813-05-0
3-bromo-5-chloro-benzaldehyde

: 1541198-33-7
C₁₂H₁₂ClF₃O₃

Guidance literature:: Multi-step reaction with 2 steps

1.1: toluene-4-sulfonic acid / toluene / 6 h / Reflux; Dean-Stark

2.1: tert.-butyl lithium / hexane; di-isopropyl ether / 0.5 h / -78 °C / Inert atmosphere

2.2: 0.5 h / -30 °C / Inert atmosphere

With tert.-butyl lithium; toluene-4-sulfonic acid; In hexane; di-isopropyl ether; toluene;