2-(3-aminopropyl)-6-phenylpyridazin-3(2H)-one

Base Information

Chemical Name:2-(3-aminopropyl)-6-phenylpyridazin-3(2H)-one
CAS No.:77375-78-1
Molecular Formula:C₁₃H₁₅N₃O
Molecular Weight:229.282
Hs Code.:
DSSTox Substance ID:DTXSID401250983

Synonyms:2-(3-aminopropyl)-6-phenylpyridazin-3(2H)-one;77375-78-1;2-(3-aminopropyl)-6-phenylpyridazin-3-one;DTXSID401250983;AKOS015956202;CS-0269872;EN300-237530;2-(3-Aminopropyl)-6-phenyl-3(2H)-pyridazinone;2-(3-aminopropyl)-6-phenyl-2,3-dihydropyridazin-3-one;F1967-0890

Suppliers and Price of 2-(3-aminopropyl)-6-phenylpyridazin-3(2H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 5 raw suppliers

Chemical Property of 2-(3-aminopropyl)-6-phenylpyridazin-3(2H)-one

Chemical Property:

XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:229.121512110
Heavy Atom Count:17
Complexity:330

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=NN(C(=O)C=C2)CCCN

Technology Process of 2-(3-aminopropyl)-6-phenylpyridazin-3(2H)-one

There total 2 articles about 2-(3-aminopropyl)-6-phenylpyridazin-3(2H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 83675-82-5
6-phenyl-2-<2-(phthalimido)propyl>-3(2H)-pyridazinone

: 77375-78-1
2-(3-Amino-propyl)-6-phenyl-2H-pyridazin-3-one

Guidance literature:: With hydrogenchloride; hydrazine hydrate; In ethanol; 1.) reflux, 5 h; 2.) pH=4.0, reflux, 2 h;

Reference yield:

: 2166-31-6
6-phenylpyridazin-3(2H)-one

: 77375-78-1
2-(3-Amino-propyl)-6-phenyl-2H-pyridazin-3-one

Guidance literature:: Multi-step reaction with 2 steps

1: 74 percent / K₂CO₃ / various solvent(s) / 6 h / Heating

2: 1.) 100 percent hydrazine hydrate, 2.) 10 percent aq. HCl / 1.) EtOH, reflux, 4 h, 2.) EtOH, reflux, 2 h

With hydrogenchloride; potassium carbonate; hydrazine hydrate; In various solvent(s);
DOI:10.1021/jm00357a012