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1-Hydroxyethylethoxypiperazine

Base Information
  • Chemical Name:1-Hydroxyethylethoxypiperazine
  • CAS No.:13349-82-1
  • Molecular Formula:C8H18N2O2
  • Molecular Weight:174.243
  • Hs Code.:29335990
  • European Community (EC) Number:603-746-0,700-022-7
  • UNII:WWT5E4KNO3
  • DSSTox Substance ID:DTXSID60158137
  • Nikkaji Number:J68.145H
  • Wikidata:Q72484083
  • Mol file:13349-82-1.mol
1-Hydroxyethylethoxypiperazine

Synonyms:1-[2-(2-Hydroxyethoxy)ethyl]piperazine;1-[2-[(2-Hydroxyethyl)oxy]ethyl]piperazine;2-[2-(1-Piperazinyl)ethoxy]ethanol;N-Hydroxyethoxyethylpiperazine;3-(Piperazin-1-yloxy)butan-2-ol;1-(2-(2-Hydroxyethoxy)Ethyl)Piperazine);

Suppliers and Price of 1-Hydroxyethylethoxypiperazine
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • 1-[2-(2-Hydroxyethoxy)ethyl]piperazine
  • 50g
  • $ 165.00
  • TCI Chemical
  • 1-[2-(2-Hydroxyethoxy)ethyl]piperazine >98.0%(GC)(T)
  • 5g
  • $ 29.00
  • TCI Chemical
  • 1-[2-(2-Hydroxyethoxy)ethyl]piperazine >98.0%(GC)(T)
  • 25g
  • $ 86.00
  • SynQuest Laboratories
  • 2-[2-(Piperazin-1-yl)ethoxy]ethan-1-ol 98.0%
  • 25 g
  • $ 158.00
  • SynQuest Laboratories
  • 2-[2-(Piperazin-1-yl)ethoxy]ethan-1-ol 98.0%
  • 5 g
  • $ 95.00
  • Sigma-Aldrich
  • 1-[2-(2-Hydroxyethoxy)ethyl]piperazine 95%
  • 5g
  • $ 44.80
  • Medical Isotopes, Inc.
  • 1-[2-(2-Hydroxyethoxy)ethyl]piperazine
  • 100 g
  • $ 1960.00
  • Matrix Scientific
  • 2-(2-Piperazin-1-ylethoxy)ethanol
  • 500mg
  • $ 95.00
  • Frontier Specialty Chemicals
  • 1-[2-(2-Hydroxyethoxy)ethyl]piperazine 95%
  • 25g
  • $ 191.00
  • Frontier Specialty Chemicals
  • 1-[2-(2-Hydroxyethoxy)ethyl]piperazine 95%
  • 5g
  • $ 47.00
Total 195 raw suppliers
Chemical Property of 1-Hydroxyethylethoxypiperazine
Chemical Property:
  • Appearance/Colour:yellow-brown oil 
  • Vapor Pressure:7.57E-05mmHg at 25°C 
  • Refractive Index:n20/D 1.497(lit.)  
  • Boiling Point:267.139 °C at 760 mmHg 
  • PKA:14.41±0.10(Predicted) 
  • Flash Point:115.362 °C 
  • PSA:44.73000 
  • Density:1.077 g/cm3 
  • LogP:-0.83280 
  • Storage Temp.:-20°C 
  • Solubility.:Acetone (Slightly), Chloroform (Slightly), Methanol (Slightly) 
  • XLogP3:-1.2
  • Hydrogen Bond Donor Count:2
  • Hydrogen Bond Acceptor Count:4
  • Rotatable Bond Count:5
  • Exact Mass:174.136827821
  • Heavy Atom Count:12
  • Complexity:105
Purity/Quality:

99% *data from raw suppliers

1-[2-(2-Hydroxyethoxy)ethyl]piperazine *data from reagent suppliers

Safty Information:
  • Pictogram(s): IrritantXi 
  • Hazard Codes:Xi 
  • Statements: 36/37/38 
  • Safety Statements: 26-37/39 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:C1CN(CCN1)CCOCCO
  • Uses 1-[2-(2-Hydroxyethoxy)ethyl]piperazine may be used in chemical synthesis. Quetiapine intermediate
Technology Process of 1-Hydroxyethylethoxypiperazine

There total 7 articles about 1-Hydroxyethylethoxypiperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With piperazine dihydrochloride; In ethanol; for 10h; Reflux; Large scale;
Guidance literature:
With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 2h;
Guidance literature:
With dipotassium peroxodisulfate; at 30 - 60 ℃; for 6h; Reagent/catalyst;
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