(4R)-3-(N-(R)-α-methylbenzylcarbamoyl)-1,2,4-trimethyl-1,4-dihydroquinoline

Base Information

Chemical Name:(4R)-3-(N-(R)-α-methylbenzylcarbamoyl)-1,2,4-trimethyl-1,4-dihydroquinoline
CAS No.:104785-57-1
Molecular Formula:C₂₁H₂₄N₂O
Molecular Weight:320.434
Hs Code.:

Synonyms:(4R)-3-(N-(R)-α-methylbenzylcarbamoyl)-1,2,4-trimethyl-1,4-dihydroquinoline

Suppliers and Price of (4R)-3-(N-(R)-α-methylbenzylcarbamoyl)-1,2,4-trimethyl-1,4-dihydroquinoline

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (4R)-3-(N-(R)-α-methylbenzylcarbamoyl)-1,2,4-trimethyl-1,4-dihydroquinoline

Chemical Property:

Purity/Quality:

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Technology Process of (4R)-3-(N-(R)-α-methylbenzylcarbamoyl)-1,2,4-trimethyl-1,4-dihydroquinoline

There total 11 articles about (4R)-3-(N-(R)-α-methylbenzylcarbamoyl)-1,2,4-trimethyl-1,4-dihydroquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 104785-55-9
2,4-dimethylquinoline 3-carboxylic acid

: 83670-13-7,104785-57-1,104785-58-2,104785-60-6
3-(N-(R)-α-methylbenzylcarbamoyl)-1,2,4-trimethyl-1,4-dihydroquinoline

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) cyanuric chloride; 2.) Et₃N / 1.) acetone, Rt, 4 h; 2.) acetone, Rt, 3 h.

2: ethanol / 168 h / 7355080 Torr / Ambient temperature

3: 46 percent / Na₂S₂O₄, 0.05 M aq borate buffer / methanol / Ambient temperature; dark, several h

With sodium dithionite; 1,3,5-trichloro-2,4,6-triazine; borate buffer; triethylamine; In methanol; ethanol;
DOI:10.1016/S0040-4020(01)87503-7

Reference yield:

: 104785-55-9
2,4-dimethylquinoline 3-carboxylic acid

: 104785-57-1
(4R)-3-(N-(R)-α-methylbenzylcarbamoyl)-1,2,4-trimethyl-1,4-dihydroquinoline

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) cyanuric chloride; 2.) Et₃N / 1.) acetone, Rt, 4 h; 2.) acetone, Rt, 3 h.

2: ethanol / 168 h / 7355080 Torr / Ambient temperature

3: 46 percent / Na₂S₂O₄, 0.05 M aq borate buffer / methanol / Ambient temperature; dark, several h

With sodium dithionite; 1,3,5-trichloro-2,4,6-triazine; borate buffer; triethylamine; In methanol; ethanol;
DOI:10.1016/S0040-4020(01)87503-7

Reference yield:

: 3886-69-9
(R)-1-phenyl-ethyl-amine

: 83670-13-7,104785-57-1,104785-58-2,104785-60-6
3-(N-(R)-α-methylbenzylcarbamoyl)-1,2,4-trimethyl-1,4-dihydroquinoline

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) cyanuric chloride; 2.) Et₃N / 1.) acetone, Rt, 4 h; 2.) acetone, Rt, 3 h.

2: ethanol / 168 h / 7355080 Torr / Ambient temperature

3: 46 percent / Na₂S₂O₄, 0.05 M aq borate buffer / methanol / Ambient temperature; dark, several h

With sodium dithionite; 1,3,5-trichloro-2,4,6-triazine; borate buffer; triethylamine; In methanol; ethanol;
DOI:10.1016/S0040-4020(01)87503-7