C₃₀H₃₁O₄P

Base Information

• Chemical Name: C₃₀H₃₁O₄P
• CAS No.: 1373432-41-7
• Molecular Formula: C₃₀H₃₁O₄P
• Molecular Weight: 486.548
• Mol file: 1373432-41-7.mol

Synonyms:C₃₀H₃₁O₄P

Chemical Property of C₃₀H₃₁O₄P

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₀H₃₁O₄P

There total 3 articles about C₃₀H₃₁O₄P which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

(R)-3-(tert-butyl)-4-(2,6-dimethoxyphenyl)-2,3 dihydrobenzo[d][1,3]oxaphosphole-3-oxide (1373432-34-8) + 2-(bromomethyl)naphthalene (3163-27-7) → C30H31O4P (1373432-41-7)

Guidance literature:

(R)-3-(tert-butyl)-4-(2,6-dimethoxyphenyl)-2,3 dihydrobenzo[d][1,3]oxaphosphole-3-oxide; With lithium diisopropyl amide; In tetrahydrofuran; at -70 ℃; for 1h; Inert atmosphere;

2-(bromomethyl)naphthalene; In tetrahydrofuran; at -70 - 20 ℃; for 3h; Inert atmosphere;

DOI:10.1021/ol300659d

Reference yield:

(R)-3-(tert-butyl)-3-oxido-2H-benzo[d][1,3]oxaphosphol-4-yl trifluoromethanesulfonate (1202032-99-2) → C30H31O4P (1373432-41-7)

Guidance literature:

Multi-step reaction with 2 steps

1.1: tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; potassium fluoride / 1,4-dioxane / Inert atmosphere

2.1: lithium diisopropyl amide / tetrahydrofuran / 1 h / -70 °C / Inert atmosphere

2.2: 3 h / -70 - 20 °C / Inert atmosphere

With potassium fluoride; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; lithium diisopropyl amide; In tetrahydrofuran; 1,4-dioxane; 1.1: Suzuki coupling;

DOI:10.1021/ol300659d

Reference yield:

(2,6-dimethoxyphenyl)boronic acid (23112-96-1) → C30H31O4P (1373432-41-7)

Guidance literature:

Multi-step reaction with 2 steps

1.1: tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; potassium fluoride / 1,4-dioxane / Inert atmosphere

2.1: lithium diisopropyl amide / tetrahydrofuran / 1 h / -70 °C / Inert atmosphere

2.2: 3 h / -70 - 20 °C / Inert atmosphere

With potassium fluoride; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; lithium diisopropyl amide; In tetrahydrofuran; 1,4-dioxane; 1.1: Suzuki coupling;

DOI:10.1021/ol300659d

upstream raw materials:

(R)-3-(tert-butyl)-3-oxido-2H-benzo[d][1,3]oxaphosphol-4-yl trifluoromethanesulfonate

(R)-3-(tert-butyl)-4-(2,6-dimethoxyphenyl)-2,3 dihydrobenzo[d][1,3]oxaphosphole-3-oxide

2-(bromomethyl)naphthalene

(2,6-dimethoxyphenyl)boronic acid

Downstream raw materials:

C₃₀H₃₁O₃P