Sodium 3,4,5,6-tetrahydroxyoxane-2-carboxylate

Base Information

• Chemical Name: Sodium 3,4,5,6-tetrahydroxyoxane-2-carboxylate
• CAS No.: 9005-38-3
• Molecular Formula: (C6H7O6Na)n
• Molecular Weight: 198.11
• Hs Code.: H7NaO6)n MOL WT.
• European Community (EC) Number: 618-415-6,934-404-1
• NCI Thesaurus Code: C84148
• RXCUI: 56446,1370451
• Mol file: 9005-38-3.mol

Synonyms:alginate;Alginate, Barium;Alginate, Calcium;Alginate, Copper;Alginate, Potassium;Alginate, Sodium;Alginate, Sodium Calcium;Alginates;alginic acid, barium salt;alginic acid, calcium salt;alginic acid, copper salt;alginic acid, potassium salt;alginic acid, sodium salt;Alloid G;barium alginate;calcium alginate;Calcium Alginate, Sodium;calginat;copper alginate;Kalrostat;Kalrostat 2;Kaltostat;poly(mannuronic acid), sodium salt;potassium alginate;sodium alginate;sodium calcium alginate;Vocoloid;Xantalgin

Chemical Property of Sodium 3,4,5,6-tetrahydroxyoxane-2-carboxylate

Chemical Property:

• Appearance/Colour: white to light yellow granules or powder
• Vapor Pressure: 6.95E-12mmHg at 25°C
• Melting Point: > 300 C
• Boiling Point: 495.2 °C at 760 mmHg
• Flash Point: 211.1 °C
• PSA: 130.28000
• Density: g/cm³
• LogP: -4.46380
• Storage Temp.: Store at RT.
• Solubility.: Slowly soluble in water forming a viscous, colloidal solution, practically insoluble in ethanol (96 per cent).
• Water Solubility.: Soluble in water. Insoluble in alcohol, chloroform and ether.
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 1
• Exact Mass: 216.02459690
• Heavy Atom Count: 14
• Complexity: 210

Purity/Quality:

99% ^*data from raw suppliers

Sodium Alginate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Not regulated UN NO.
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: S24/25:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Biological Agents -> Plant Oils and Extracts
• Canonical SMILES: C1(C(C(OC(C1O)O)C(=O)[O-])O)O.[Na+]
• Recent ClinicalTrials: Primary carE PPi dEprescRibing Trial
• Recent EU Clinical Trials: Randomized controlled clinical trial to evaluate the efficacy of alginates in washout of proton pump inhibitor therapy with consideration of compliance and symptom burden in patients with gastroesophageal reflux disease (GERD).
• Recent NIPH Clinical Trials: Clinical trial of submucosal injection color adjustment in POEM
• Extraction and Structure: Sodium alginate is a natural polysaccharide extracted from brown algae. It is a linear copolymer composed of 尾-D-mannuronic acid (M) and 伪-L-guluronic acid (G) residues linked by 1 鈫? 4 glycosidic bonds.; Sodium alginate can contain acetyl substituents, and the amount may vary among products from different sources.
• Properties: Sodium alginate exhibits high biocompatibility, biodegradability, and renewability. It is hydrophilic and can form colloidal dispersions in both cold and hot water.; In the presence of divalent cations like calcium, it forms a three-dimensional network (gel), described by the "egg box" model.; Despite its advantageous properties, sodium alginate's mechanical strength, stability, and heat resistance are relatively low.
• Uses: Sodium alginate is utilized in various industries, including pharmaceuticals, food, tissue engineering, and others. In pharmaceuticals, it is used for drug delivery systems (DDS), mucoadhesive systems, microspheres, microcapsules, tablets, and sutures. It serves as a stabilizer, viscosifier, and gelling or film-forming agent in food products. In the pharmaceutical industry, it functions as a suspending agent, tablet binder, taste masker, and controlled-release matrix.
• Modification and Characterization: Various characterization techniques such as X-ray photoelectron spectroscopy (XPS), Fourier transform infrared spectroscopy (FT-IR), and scanning electron microscopy (SEM) are employed to analyze sodium alginate and its interactions with heavy metal ions. Surface grafting, cross-linking, and composite formation with other materials are common methods used to modify sodium alginate to enhance its properties for specific applications.