N,N'-bis<4-(tosylamino)butyl>-N,N'-ditosyl-1,3-propanediamine

Base Information

• Chemical Name: N,N'-bis<4-(tosylamino)butyl>-N,N'-ditosyl-1,3-propanediamine
• CAS No.: 121821-06-5
• Molecular Formula: C₃₉H₅₂N₄O₈S₄
• Molecular Weight: 833.128
• Mol file: 121821-06-5.mol

Synonyms:N,N'-bis<4-(tosylamino)butyl>-N,N'-ditosyl-1,3-propanediamine

Chemical Property of N,N'-bis<4-(tosylamino)butyl>-N,N'-ditosyl-1,3-propanediamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N,N'-bis<4-(tosylamino)butyl>-N,N'-ditosyl-1,3-propanediamine

There total 4 articles about N,N'-bis<4-(tosylamino)butyl>-N,N'-ditosyl-1,3-propanediamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N,N'-bis(4-formamidobutyl)-N,N'-ditosyl-1,3-propanediamine (121821-17-8) → N,N'-bis<4-(tosylamino)butyl>-N,N'-ditosyl-1,3-propanediamine (121821-06-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 2M HCl / ethanol / 4 h / 80 °C

2: Et₃N, pyridine / 4 h / Ambient temperature

With pyridine; hydrogenchloride; triethylamine; In ethanol;

DOI:10.1246/bcsj.62.198

Reference yield:

N,N'-bis(4-phthalimidobutyl)-N,N'-ditosyl-1,3-propanediamine (121821-30-5) → N,N'-bis<4-(tosylamino)butyl>-N,N'-ditosyl-1,3-propanediamine (121821-06-5)

Guidance literature:

Multi-step reaction with 3 steps

1: 92 percent / N₂H₄*H₂O / 23 h / 75 °C

2: 2M HCl / ethanol / 4 h / 80 °C

3: Et₃N, pyridine / 4 h / Ambient temperature

With pyridine; hydrogenchloride; hydrazine hydrate; triethylamine; In ethanol;

DOI:10.1246/bcsj.62.198

Reference yield:

p-toluenesulfonyl chloride (98-59-9) + C25H40N4O4S2*2ClH → N,N'-bis<4-(tosylamino)butyl>-N,N'-ditosyl-1,3-propanediamine (121821-06-5)

Guidance literature:

With pyridine; triethylamine; for 4h; Yield given; Ambient temperature;

DOI:10.1246/bcsj.62.198

upstream raw materials:

5,9-diaza-1,13-tridecanediamine

toluene-4-sulfonic acid

p-toluenesulfonyl chloride

N,N'-bis(4-formamidobutyl)-N,N'-ditosyl-1,3-propanediamine

Downstream raw materials:

3-Dodecyl-1,5,10,14-tetrakis-(toluene-4-sulfonyl)-1,5,10,14-tetraaza-cyclooctadecane

4,9,13,18-tetratosyl-N¹,N¹:N²¹,N²¹-diphthaloyl-4,9,13,18-tetraazaheneicosane-1,21-diamine

4,9,13,18-tetratosyl-N¹,N²¹-diformyl-4,9,13,18-tetraazaheneicosane-1,21-diamine

N¹,N²¹,4,9,13,18-hexatosyl-4,9,13,18-tetraazaheneicosane-1,21-diamine