4-Chloro-2-(trifluoromethyl)aniline

Base Information

Chemical Name:4-Chloro-2-(trifluoromethyl)aniline
CAS No.:445-03-4
Molecular Formula:C7H5ClF3N
Molecular Weight:195.572
Hs Code.:29214300
European Community (EC) Number:207-151-3
DSSTox Substance ID:DTXSID6060000
Nikkaji Number:J1.533D
Wikidata:Q72434337
Mol file:445-03-4.mol

Synonyms:4-chloro-2-(trifluoromethyl)aniline

Suppliers and Price of 4-Chloro-2-(trifluoromethyl)aniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TCI Chemical
2-Amino-5-chlorobenzotrifluoride >98.0%(GC)
25g
$ 22.00

TCI Chemical
2-Amino-5-chlorobenzotrifluoride >98.0%(GC)
500g
$ 170.00

SynQuest Laboratories
2-Amino-5-chlorobenzotrifluoride 95%
500 g
$ 105.00

SynQuest Laboratories
2-Amino-5-chlorobenzotrifluoride 95%
100 g
$ 35.00

Sigma-Aldrich
4-Chloro-2-(trifluoromethyl)aniline 97%
25g
$ 37.00

Oakwood
2-Amino-5-chlorobenzotrifluoride 97%
1g
$ 10.00

Oakwood
2-Amino-5-chlorobenzotrifluoride 97%
5g
$ 11.00

Oakwood
2-Amino-5-chlorobenzotrifluoride 97%
100g
$ 50.00

Oakwood
2-Amino-5-chlorobenzotrifluoride 97%
500g
$ 100.00

Matrix Scientific
2-Amino-5-chlorobenzotrifluoride 97%
500g
$ 109.00

Total 154 raw suppliers

Chemical Property of 4-Chloro-2-(trifluoromethyl)aniline

Chemical Property:

Appearance/Colour:Clear yellow liquid
Vapor Pressure:0.0145mmHg at 25°C
Melting Point:8.8 °C
Refractive Index:n20/D 1.507(lit.)
Boiling Point:213.2 °C at 760 mmHg
PKA:0.83±0.10(Predicted)
Flash Point:82.7 °C
PSA：26.02000
Density:1.425 g/cm³
LogP:3.52220
Storage Temp.:0-6°C
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:195.0062613
Heavy Atom Count:12
Complexity:159

Purity/Quality:

99% ^*data from raw suppliers

2-Amino-5-chlorobenzotrifluoride >98.0%(GC) ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn, Xi
Hazard Codes:Xn,Xi
Statements: 20/21/22-33-36/37/38-41-22
Safety Statements: 26-36-37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1Cl)C(F)(F)F)N
Uses 4-Chloro-2-(trifluoromethyl)aniline was used in the synthesis of 2-amino-5-chloro 3-(trifluoromethyl)benzenethiol. 2-Amino-5-chlorobenzotrifluoride is a biologically active compound and useful building block. It can be transformed into a variety of valuable fluorine-containing molecules and heterocyclic compounds.

Technology Process of 4-Chloro-2-(trifluoromethyl)aniline

There total 18 articles about 4-Chloro-2-(trifluoromethyl)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 887144-94-7
Togni's reagent II

: 106-47-8
4-chloro-aniline

: 445-03-4
4-chloro-2-(trifluoromethyl)aniline

Guidance literature:: With potassium carbonate; In acetonitrile; at 75 ℃; for 6h; Schlenk technique; Inert atmosphere;
DOI:10.1016/j.tetlet.2019.151538

Reference yield: 90.0%

: 88-17-5
2-(trifluoromethyl)benzenamine

: 445-03-4
4-chloro-2-(trifluoromethyl)aniline

Guidance literature:: With copper dichloride; 1-hexyl-3-methylimidazol-1-ium chloride; at 40 ℃; for 6h; regioselective reaction;
DOI:10.3762/bjoc.8.84