3,3'-[1,4-phenylenebis(sulfinyl)]bispropanoic acid 1,1'-dimethyl ester

Base Information

• Chemical Name: 3,3'-[1,4-phenylenebis(sulfinyl)]bispropanoic acid 1,1'-dimethyl ester
• CAS No.: 1379507-93-3
• Molecular Formula: C₁₆H₂₂O₆S₂
• Molecular Weight: 374.479
• Mol file: 1379507-93-3.mol

Synonyms:3,3'-[1,4-phenylenebis(sulfinyl)]bispropanoic acid 1,1'-dimethyl ester

Chemical Property of 3,3'-[1,4-phenylenebis(sulfinyl)]bispropanoic acid 1,1'-dimethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,3'-[1,4-phenylenebis(sulfinyl)]bispropanoic acid 1,1'-dimethyl ester

There total 2 articles about 3,3'-[1,4-phenylenebis(sulfinyl)]bispropanoic acid 1,1'-dimethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1,4-di-{[(2-methoxycarbonylethyl)thio]methyl}benzene (1379507-96-6) → 3,3'-[1,4-phenylenebis(sulfinyl)]bispropanoic acid 1,1'-dimethyl ester (1379507-93-3)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at -78 ℃;

DOI:10.1016/j.bmc.2012.03.070

Reference yield:

1,4-bis(mercaptomethyl)benzene (105-09-9) → 3,3'-[1,4-phenylenebis(sulfinyl)]bispropanoic acid 1,1'-dimethyl ester (1379507-93-3)

Guidance literature:

Multi-step reaction with 2 steps

1: N-benzyl-trimethylammonium hydroxide / tetrahydrofuran / -78 °C

2: 3-chloro-benzenecarboperoxoic acid / dichloromethane / -78 °C

With N-benzyl-trimethylammonium hydroxide; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; dichloromethane;

DOI:10.1080/17415993.2015.1024679

Reference yield: 88.0%

3,3'-[1,4-phenylenebis(sulfinyl)]bispropanoic acid 1,1'-dimethyl ester (1379507-93-3) + 2-thiocytosine (333-49-3,139424-17-2) → 2,2'-[1,4-phenylenebis(methylenedithio)]bis-4-pyrimidinamine

Guidance literature:

In 1,4-dioxane; at 101 ℃; for 3.66667h; Solvent; Temperature;

DOI:10.1080/17415993.2015.1024679

upstream raw materials:

1,4-di-{[(2-methoxycarbonylethyl)thio]methyl}benzene

1,4-bis(mercaptomethyl)benzene

Downstream raw materials:

1,4-di-{[(β-D-glucopyranosyl)dithio]methyl}benzene

1,4-di-{[(β-D-galactopyranosyl)dithio]methyl}benzene

1-{[(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)dithio]methyl}-4-{[(2-methoxycarbonylethyl)sulfinyl]methyl}benzene

1,4-di-{[(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)dithio]methyl}benzene