N-Acetyl-2-deoxy-2-amino-galactose

Base Information

• Chemical Name: N-Acetyl-2-deoxy-2-amino-galactose
• CAS No.: 14215-68-0
• Deprecated CAS: 103618-08-2,31258-50-1
• Molecular Formula: C₈H₁₅NO₆
• Molecular Weight: 221.21
• Hs Code.: 29329990
• UNII: 00C01APN10
• DSSTox Substance ID: DTXSID70884733
• Nikkaji Number: J382.936G
• Wikipedia: N-Acetylgalactosamine
• Wikidata: Q285835
• Metabolomics Workbench ID: 37138
• ChEMBL ID: CHEMBL1230702
• Mol file: 14215-68-0.mol

Synonyms:2 Acetamido 2 D galactopyranose;2 Acetamido 2 Deoxy D Galactose;2 Acetamido 2 Deoxygalactose;2-Acetamido-2-D-galactopyranose;2-Acetamido-2-Deoxy-D-Galactose;2-Acetamido-2-Deoxygalactose;Acetylgalactosamine;N Acetyl D Galactosamine;N-Acetyl-D-Galactosamine

Chemical Property of N-Acetyl-2-deoxy-2-amino-galactose

Chemical Property:

• Appearance/Colour: white to off-white fine crystalline powder
• Vapor Pressure: 7.12E-19mmHg at 25°C
• Melting Point: 158-162 °C
• Refractive Index: 85 ° (C=1, H2O)
• Boiling Point: 595.4 °C at 760 mmHg
• PKA: 12.04±0.70(Predicted)
• Flash Point: 313.9 °C
• PSA: 119.25000
• Density: 1.5 g/cm³
• LogP: -2.68670
• Storage Temp.: 2-8°C
• Solubility.: Methanol (Slightly, Sonicated), Water (Slightly)
• Water Solubility.: almost transparency
• XLogP3: -1.7
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 2
• Exact Mass: 221.08993720
• Heavy Atom Count: 15
• Complexity: 235

Purity/Quality:

98% min ^*data from raw suppliers

N-Acetyl-D-galactosamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)NC1C(C(C(OC1O)CO)O)O
• Isomeric SMILES: CC(=O)N[C@@H]1[C@H]([C@H]([C@H](O[C@@H]1O)CO)O)O
• Uses: N-Acetyl-D-galactosamine is a bio-activated reporters to visualize.

Technology Process of N-Acetyl-2-deoxy-2-amino-galactose

There total 136 articles about N-Acetyl-2-deoxy-2-amino-galactose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(+)-D-glucosamine hydrochloride (1078691-95-8) + acetic anhydride (108-24-7) → N-Acetyl-D-glucosamine (7512-17-6,72-87-7,1136-42-1,1136-44-3,6082-29-7,6730-06-9,7772-94-3,10036-64-3,14131-60-3,14131-64-7,14131-68-1,14215-68-0,62057-49-2,62057-50-5,62057-51-6,62057-52-7,62057-53-8,62057-54-9,62057-55-0,62057-56-1,62075-50-7,62137-54-6,134451-97-1,134522-12-6,148347-16-4)

Guidance literature:

With sodium hydrogencarbonate; In water; at 20 ℃; for 1.5h;

DOI:10.1002/ejoc.200300254

Reference yield:

4-nitrophenyl N-acetyl-β-D-glucosaminide (3459-18-5,50645-66-4) → 4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) + N-Acetyl-D-glucosamine (7512-17-6,72-87-7,1136-42-1,1136-44-3,6082-29-7,6730-06-9,7772-94-3,10036-64-3,14131-60-3,14131-64-7,14131-68-1,14215-68-0,62057-49-2,62057-50-5,62057-51-6,62057-52-7,62057-53-8,62057-54-9,62057-55-0,62057-56-1,62075-50-7,62137-54-6,134451-97-1,134522-12-6,148347-16-4)

Guidance literature:

With chitinase from Streptomyces griseus; In phosphate buffer; at 30 ℃; for 1h; pH=6.0; Product distribution; Enzymatic reaction;

DOI:10.1016/S0008-6215(99)00002-6

Reference yield:

acetic acid (64-19-7,77671-22-8) + p-nitrophenyl 2-amino-2-deoxy-β-D-glucopyranosyl-(1->4)-2-acetamido-2-deoxy-β-D-glucopyranoside (219727-01-2) → 4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) + N-Acetyl-D-glucosamine (7512-17-6,72-87-7,1136-42-1,1136-44-3,6082-29-7,6730-06-9,7772-94-3,10036-64-3,14131-60-3,14131-64-7,14131-68-1,14215-68-0,62057-49-2,62057-50-5,62057-51-6,62057-52-7,62057-53-8,62057-54-9,62057-55-0,62057-56-1,62075-50-7,62137-54-6,134451-97-1,134522-12-6,148347-16-4)

Guidance literature:

With β-N-acetylhexosaminidase; chitin deacetylase; at 30 ℃; pH=7.0; Further Variations:; reaction time; Product distribution;

DOI:10.1016/S0008-6215(99)00213-X

upstream raw materials:

2-methyl-(1,2-dideoxy-5,6-O-isopropylidene-α-D-glucofurano)-<2,1-d>-2-oxazoline

N-acetyl neuraminic acid

uridine 5'-diphospho-N-acetylglucosamine

methanol

Downstream raw materials:

1,3,4,6-tetra-O-acetyl-2-acetamido-2-deoxy-α,β-D-mannopyranose

β-D-galactopyranosyl-(1->6)-2-acetamido-2-deoxy-β-D-mannopyranose

β-D-galactopyranosyl-(1->6)-2-acetamido-2-deoxy-α-D-mannopyranose

N-Acetyl-D-glucosamine