methyl 2-deoxy-3,4-O-isopropylidene-5-O-methanesulfonyl-2-[(9-phenyl-9-fluorenyl)-amino]-D-arabinonate

Base Information

Chemical Name:methyl 2-deoxy-3,4-O-isopropylidene-5-O-methanesulfonyl-2-[(9-phenyl-9-fluorenyl)-amino]-D-arabinonate
CAS No.:302593-20-0
Molecular Formula:C₂₉H₃₁NO₇S
Molecular Weight:537.634
Hs Code.:

Synonyms:methyl 2-deoxy-3,4-O-isopropylidene-5-O-methanesulfonyl-2-[(9-phenyl-9-fluorenyl)-amino]-D-arabinonate

Suppliers and Price of methyl 2-deoxy-3,4-O-isopropylidene-5-O-methanesulfonyl-2-[(9-phenyl-9-fluorenyl)-amino]-D-arabinonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 2-deoxy-3,4-O-isopropylidene-5-O-methanesulfonyl-2-[(9-phenyl-9-fluorenyl)-amino]-D-arabinonate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 2-deoxy-3,4-O-isopropylidene-5-O-methanesulfonyl-2-[(9-phenyl-9-fluorenyl)-amino]-D-arabinonate

There total 7 articles about methyl 2-deoxy-3,4-O-isopropylidene-5-O-methanesulfonyl-2-[(9-phenyl-9-fluorenyl)-amino]-D-arabinonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 124-63-0
methanesulfonyl chloride

: 302593-18-6
methyl 2-deoxy-3,4-O-isopropylidene-2-[(9-phenyl-9-fluorenyl)-amino]-D-arabinonate

: 302593-20-0
methyl 2-deoxy-3,4-O-isopropylidene-5-O-methanesulfonyl-2-[(9-phenyl-9-fluorenyl)-amino]-D-arabinonate

Guidance literature:: With triethylamine; In tetrahydrofuran; at 20 ℃; for 0.25h;
DOI:10.1016/S0040-4020(01)01070-5

Reference yield:

: Methyl 2-azido-2-deoxy-3,4:5,6-O-diisopropylidene-L-idonate

: 302593-20-0
methyl 2-deoxy-3,4-O-isopropylidene-5-O-methanesulfonyl-2-[(9-phenyl-9-fluorenyl)-amino]-D-arabinonate

Guidance literature:: Multi-step reaction with 6 steps

1: H₂ / 10 percent Pd/C / ethyl acetate / 5 h / 20 °C

2: 6.14 g / Pb(NO₃)2; Et₃N / CH₂Cl₂ / 48 h / 20 °C

3: 95 percent / Dowex 50W-X₈ / methanol / 20 h / 20 °C

4: aq. NaIO₄ / ethanol / 1 h / 20 °C

5: 0.80 g / NaBH₄ / aq. ethanol / 0.5 h / 0 °C

6: 96 percent / Et₃N / tetrahydrofuran / 0.25 h / 0 °C

With sodium tetrahydroborate; sodium periodate; lead(II) nitrate; Dowex 50W-X₈; hydrogen; triethylamine; palladium on activated charcoal; In tetrahydrofuran; methanol; ethanol; dichloromethane; ethyl acetate; 1: Reduction / 2: Substitution / 3: Ring cleavage / 4: Oxidation / 5: Reduction / 6: Substitution;
DOI:10.1055/s-2000-6408

Reference yield:

: 55135-66-5
9-bromo-9-phenyl-9H-fluorene

: 302593-20-0
methyl 2-deoxy-3,4-O-isopropylidene-5-O-methanesulfonyl-2-[(9-phenyl-9-fluorenyl)-amino]-D-arabinonate

Guidance literature:: Multi-step reaction with 5 steps

1: 6.14 g / Pb(NO₃)2; Et₃N / CH₂Cl₂ / 48 h / 20 °C

2: 95 percent / Dowex 50W-X₈ / methanol / 20 h / 20 °C

3: aq. NaIO₄ / ethanol / 1 h / 20 °C

4: 0.80 g / NaBH₄ / aq. ethanol / 0.5 h / 0 °C

5: 96 percent / Et₃N / tetrahydrofuran / 0.25 h / 0 °C

With sodium tetrahydroborate; sodium periodate; lead(II) nitrate; Dowex 50W-X₈; triethylamine; In tetrahydrofuran; methanol; ethanol; dichloromethane; 1: Substitution / 2: Ring cleavage / 3: Oxidation / 4: Reduction / 5: Substitution;
DOI:10.1055/s-2000-6408