Cyclopropanesulfonamide

Base Information

• Chemical Name: Cyclopropanesulfonamide
• CAS No.: 154350-29-5
• Molecular Formula: C3H7NO2S
• Molecular Weight: 121.16
• Hs Code.: 2935009090
• Mol file: 154350-29-5.mol

Synonyms:Cyclopropanesulfonyl amide;

Chemical Property of Cyclopropanesulfonamide

Chemical Property:

• Appearance/Colour: White-like powder
• Vapor Pressure: 0.01mmHg at 25°C
• Melting Point: 95-98 °C(lit.)
• Refractive Index: 1.54
• Boiling Point: 263.091 °C at 760 mmHg
• PKA: 10.69±0.20(Predicted)
• Flash Point: 112.914 °C
• PSA: 68.54000
• Density: 1.446 g/cm³
• LogP: 1.21840
• Storage Temp.: Sealed in dry,Room Temperature
• Water Solubility.: Soluble in water.

Purity/Quality:

99% ^*data from raw suppliers

Cyclopropanesulfonamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22-38
• Safety Statements: 26-28-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Cyclopropanesulfonamide is used as fine chemicals to the pharmaceutical, agrochemical, aroma, polymer and electronic industries.

Technology Process of Cyclopropanesulfonamide

There total 10 articles about Cyclopropanesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

cyclopropanesulfonyl chloride (139631-62-2) → cyclopropanesulphonamide (154350-29-5)

Guidance literature:

With ammonia; In tetrahydrofuran; at 0 - 20 ℃; for 24h; Product distribution / selectivity;

Reference yield: 95.0%

tert-butyl (cyclopropylsulfonyl)carbamate (681808-26-4) → cyclopropanesulphonamide (154350-29-5)

Guidance literature:

With trifluoroacetic acid; at 20 ℃; for 16h; Product distribution / selectivity;

Reference yield: 95.0%

→ cyclopropanesulphonamide (154350-29-5)

Guidance literature:

upstream raw materials:

N-t-butyl-1-cyclopropylsulfonamide

cyclopropanesulfonyl chloride

tert-butyl (cyclopropylsulfonyl)carbamate

benzyl bromide

Downstream raw materials:

tert-butyl ((1R,2S)-1-{[(cyclopropylsulfonyl)amino]carbonyl}-2-vinylcyclopropyl)carbamate

2(S)-(1(R)-cyclopropanesulfonylamino-carbonyl-2(S)-vinylcyclopropylcarbamoyl)-4(R)-(7-methoxy-2-phenylquinolin-4-yloxy)-pyrrolidine-1-carboxylic acid tert-butyl ester

(3R,5S,8S)-8-butyl-N-((1R,2S)-1-{[(cyclopropylsulfonyl)amino]carbonyl}-2-vinylcyclopropyl)-7,10-dioxo-22-phenyl-2,11-dioxa-6,9,21-triazatetracyclo[15.6.2.1-3,6-.0-20,24-]hexacosa-1⁽²³⁾,17,19,21,24-pentaene-5-carboxamide

cyclopropanesulfonic acid [17-(2-methoxy-6-phenylpyrimidin-4-yloxy)-13-methyl-2,14-dioxo-3,13-diaza-tricyclo[13.3.0.0*4,6*]octadec-7-ene-4-carbonyl]-amide

Refernces

• 1、 Huang, Binbin,Yang, Chao,Zhou, Jia,Xia, Wujiong. "Electrochemically generatedN-iodoaminium species as key intermediates for selective methyl sulphonylimination of tertiary amines". supporting information. p. 5010 - 5013. Retrieved 2020/05/18.
• 2、 -. "THIAZOLIDINONE COMPOUNDS AND USE THEREOF". Paragraph 0054; 0401-0402. . Retrieved 2017/09/21.