CID 9862773

Base Information

• Chemical Name: CID 9862773
• CAS No.: 49557-75-7
• Molecular Formula: C14H24N6O4
• Molecular Weight: 340.382
• Hs Code.: 2933290090
• Mol file: 49557-75-7.mol

Synonyms:

Chemical Property of CID 9862773

Chemical Property:

• Appearance/Colour: White powder
• Vapor Pressure: 2.86E-29mmHg at 25°C
• Refractive Index: 1.582
• Boiling Point: 831 °C at 760 mmHg
• PKA: 3.11±0.10(Predicted)
• Flash Point: 456.4 °C
• PSA: 176.22000
• Density: 1.324 g/cm³
• LogP: 0.27650
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• Solubility.: Aqueous Acid (Slightly), DMSO (Slightly)
• XLogP3: -3.7
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 10
• Exact Mass: 340.18590327
• Heavy Atom Count: 24
• Complexity: 428

Purity/Quality:

99% BY HPLC ^*data from raw suppliers

Glycyl-L-histidyl-L-lysine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=C(NC=N1)CC(C(=O)NC(CCCC[NH3+])C(=O)[O-])NC(=O)CN
• Isomeric SMILES: C1=C(NC=N1)C[C@@H](C(=O)N[C@@H](CCCC[NH3+])C(=O)[O-])NC(=O)CN
• Description: Copper peptide GHK-Cu is a naturally occurring copper complex of the tripeptide glycyl-L-histidyl-L-lysine. The tripeptide has strong affinity for copper(II) and was first isolated from human plasma. It can be found also in saliva and urine.
• Uses: Copper Peptide(GHK-Cu) can be used as skin antiaging agents. Glycyl-L-histidyl-L-lysine is a liver cell growth factor and an asynthetic hepatotrophic agent that stimulates hepatic erythropoietic factor production.

Technology Process of CID 9862773

There total 3 articles about CID 9862773 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

N-(fluoren-9-ylmethoxycarbonyl)glycine (29022-11-5) + Fmoc-Lys(tert-butoxycarbonyl) (71989-26-9) + Fmoc-His(Trt)-OH (109425-51-6) → glycyl-L-histidyl-L-lysine (49557-75-7)

Guidance literature:

Multistep reaction;

DOI:10.1039/b410402a

Reference yield:

→ glycyl-L-histidyl-L-lysineamide + glycyl-L-histidyl-L-lysine (49557-75-7)

Guidance literature:

Reference yield:

→ glycyl-L-histidyl-L-lysine (49557-75-7)

Guidance literature:

upstream raw materials:

N-(fluoren-9-ylmethoxycarbonyl)glycine

Fmoc-Lys(tert-butoxycarbonyl)

Fmoc-His(Trt)-OH

Refernces

• 1、 -. "Solid phase method for synthesis peptide-spacer-lipid conjugates, conjugates synthesized thereby and targeted liposomes containing the same". Page 12; 13. . Retrieved 2010/02/03.
• 2、 -. "Bursopoietin". . . Retrieved 2008/06/13.