(Z)-3-(Naphthalen-1-ylselanyl)-3-phenyl-acrylic acid methyl ester

Base Information

• Chemical Name: (Z)-3-(Naphthalen-1-ylselanyl)-3-phenyl-acrylic acid methyl ester
• CAS No.: 84144-10-5
• Molecular Formula: C₂₀H₁₆O₂Se
• Molecular Weight: 367.306
• Mol file: 84144-10-5.mol

Synonyms:(Z)-3-(Naphthalen-1-ylselanyl)-3-phenyl-acrylic acid methyl ester

Chemical Property of (Z)-3-(Naphthalen-1-ylselanyl)-3-phenyl-acrylic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (Z)-3-(Naphthalen-1-ylselanyl)-3-phenyl-acrylic acid methyl ester

There total 2 articles about (Z)-3-(Naphthalen-1-ylselanyl)-3-phenyl-acrylic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-Bromonaphthalene (90-11-9) → (Z)-3-(Naphthalen-1-ylselanyl)-3-phenyl-acrylic acid methyl ester (84144-10-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) magnesium turnings, iodine, 2.) selenium shot / 1.) THF, reflux, 0.5 h, 2.) reflux, 3 h

2: 1.) sodium borohydride / 1.) THF, ethanol, 2.) room temperature, 0.5 h

With selenium; sodium tetrahydroborate; iodine; magnesium;

DOI:10.1021/ja00342a041

Reference yield:

2-bis[3,5bis(trifluoromethyl)phenyl]diselane (1787-80-0) + phenylpropynoic acid methyl ester (4891-38-7) → (Z)-3-(Naphthalen-1-ylselanyl)-3-phenyl-acrylic acid methyl ester (84144-10-5)

Guidance literature:

With sodium tetrahydroborate; Yield given. Multistep reaction; 1.) THF, ethanol, 2.) room temperature, 0.5 h;

DOI:10.1021/ja00342a041

Reference yield: 92.0%

(Z)-3-(Naphthalen-1-ylselanyl)-3-phenyl-acrylic acid methyl ester (84144-10-5) → (Z)-3-(Naphthalen-1-ylselanyl)-3-phenyl-acrylic acid (84144-19-4)

Guidance literature:

With potassium hydroxide; In ethanol; at 50 ℃; for 2h;

DOI:10.1021/ja00342a041

upstream raw materials:

2-bis[3,5bis(trifluoromethyl)phenyl]diselane

phenylpropynoic acid methyl ester

1-Bromonaphthalene

Downstream raw materials:

(Z)-3-(Naphthalen-1-ylselanyl)-3-phenyl-acrylic acid

(Z)-3-(Naphthalen-1-ylselanyl)-3-phenyl-acryloyl chloride

3-phenyl-5-(1-naphthyl)-1,2-oxaselenol-1-ium chloride