(2S,4S)-1-tert-butyl 2-methyl 4-(3-nitrophenylsulfonyloxy)pyrrolidine-1,2-dicarboxylate

Base Information

• Chemical Name: (2S,4S)-1-tert-butyl 2-methyl 4-(3-nitrophenylsulfonyloxy)pyrrolidine-1,2-dicarboxylate
• CAS No.: 1252633-25-2
• Molecular Formula: C₁₇H₂₂N₂O₉S
• Molecular Weight: 430.436

Synonyms:(2S,4S)-1-tert-butyl 2-methyl 4-(3-nitrophenylsulfonyloxy)pyrrolidine-1,2-dicarboxylate

Chemical Property of (2S,4S)-1-tert-butyl 2-methyl 4-(3-nitrophenylsulfonyloxy)pyrrolidine-1,2-dicarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2S,4S)-1-tert-butyl 2-methyl 4-(3-nitrophenylsulfonyloxy)pyrrolidine-1,2-dicarboxylate

There total 1 articles about (2S,4S)-1-tert-butyl 2-methyl 4-(3-nitrophenylsulfonyloxy)pyrrolidine-1,2-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(2S,4S)-N-tert-butoxycarbonyl-4-hydroxyproline methyl ester (74844-91-0,114676-69-6,135042-17-0,227935-38-8,102195-79-9) + 3-nitrobenzenesulphonyl chloride (121-51-7) → (2S,4S)-1-tert-butyl 2-methyl 4-(3-nitrophenylsulfonyloxy)pyrrolidine-1,2-dicarboxylate (1252633-25-2)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃; Inert atmosphere;

Reference yield: 86.0%

2-chlorothiphenol (6320-03-2) + (2S,4S)-1-tert-butyl 2-methyl 4-(3-nitrophenylsulfonyloxy)pyrrolidine-1,2-dicarboxylate (1252633-25-2) → 1-tert-butyl 2-methyl (2S,4R)-4-[(2-chlorophenyl)sulfanyl]pyrrolidine-1,2-dicarboxylate (1252632-04-4)

Guidance literature:

With triethylamine; at 20 ℃; for 48h; Inert atmosphere;

Reference yield:

(2S,4S)-1-tert-butyl 2-methyl 4-(3-nitrophenylsulfonyloxy)pyrrolidine-1,2-dicarboxylate (1252633-25-2) + 2-chloro-4-fluorobenzenethiol (175277-99-3) → 1-tert-butyl 2-methyl (2S,4R)-4-[(2-chloro-4-fluorophenyl)sulfanyl]pyrrolidine-1,2-dicarboxylate (1252633-26-3)

Guidance literature:

With triethylamine; In propiononitrile; at 110 ℃; for 18h;

upstream raw materials:

(2S,4S)-N-tert-butoxycarbonyl-4-hydroxyproline methyl ester

3-nitrobenzenesulphonyl chloride

Downstream raw materials:

1-tert-butyl 2-methyl (2S,4R)-4-[(2-chloro-4-fluorophenyl)sulfanyl]pyrrolidine-1,2-dicarboxylate

1-tert-butyl 2-methyl (2S,4R)-4-[(2-chlorophenyl)sulfanyl]pyrrolidine-1,2-dicarboxylate

(2S,4R)-1-(1-(4-chlorophenyl)cyclopropanecarbonyl)-4-(2-chlorophenylsulfonyl)pyrrolidine-2-carboxylic acid

(2S,4R)-1-tert-butyl 2-methyl 4-(2-chlorophenylsulfonyl)pyrrolidine-1,2-dicarboxylate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1252633-25-2 (2S,4S)-1-tert-butyl 2-methyl 4-(3-nitrophenylsulfonyloxy)pyrrolidine-1,2-dicarboxylate

Send

Send

Metric Ton KG G Pound L ML

Send

Send