6320-03-2

Basic information

• Product Name: 2-CHLOROTHIOPHENOL
• Synonyms: O-CHLOROTHIOPHENOL;2-CHLOROBENZENETHIOL;2-CHLOROTHIOPHENOL;1-CHLORO-2-MERCAPTOBENZENE;2-chloro-benzenethio;Benzenethiol, o-chloro-;Benzenethiol,2-chloro-;o-Chlorobenzenethiol
• CAS NO: 6320-03-2
• Molecular Formula: C₆H₅ClS
• Molecular Weight: 144.62
• EINECS: 228-667-5
• Product Categories: Phenol&Thiophenol&Mercaptan;Phenoles and thiophenoles
• Mol File: 6320-03-2.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 205-206 °C260 mm Hg(lit.)
• Flash Point: 191 °F
• Appearance: Clear slightly yellow/Liquid
• Density: 1.275 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.344mmHg at 25°C
• Refractive Index: n20/D 1.6029(lit.)
• PKA: 5.90±0.43(Predicted)
• Water Solubility: 2.4g/L at 20℃
• Sensitive: Stench/Lachrymatory
• BRN: 1209665
• CAS DataBase Reference: 2-CHLOROTHIOPHENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLOROTHIOPHENOL(6320-03-2)
• EPA Substance Registry System: 2-CHLOROTHIOPHENOL(6320-03-2)

Safety Data

• Hazard Codes: C
• Statements: 34-36/37-20/21/22
• Safety Statements: 26-36/37/39-45-27
• RIDADR: UN 3265 8/PG 2
• WGK Germany: 3
• F: 9-13-23-19
• TSCA: T
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 6320-03-2(Hazardous Substances Data)

Usage

Chemical Properties

Clear slightly yellow liquid

Uses

2-Chlorothiophenol has been used in the synthesis of bis (2-chlorophenyl) analog of aromatic disulfide.

General Description

2-Chlorothiophenol undergoes multi-component condensation reaction with chloroacetyl chloride and primary aliphatic amines via Smile rearrrangement.

Flammability and Explosibility

Nonflammable

InChI:InChI=1/C6H5ClS/c7-5-3-1-2-4-6(5)8/h1-4,8H/p-1

Upstream product

• 95-51-2 o-chloroaniline 
• 95-50-1 1,2-dichloro-benzene 
• 75-08-1 ethanethiol 
• 18619-18-6 (2-chloro-phenylsulfanyl)-acetic acid 
• 89-90-7 2-chlorobenzenediazonium chloride 
• 140-89-6 potassium ethyl xanthogenate 
• 694-80-4 2-bromo-1-chlorobenzene 
• 7647-01-0 hydrogenchloride 
• 2905-23-9 2-chlorophenylsulfonyl chloride 
• 1956-97-4 2-chlorobenzenediazonium tetrafluoroborate 

Downstream Products

• 63918-04-7 diethyl-[2-(2-chloro-phenylsulfanyl)-ethyl]-amine 
• 33668-01-8 (2-chloro-phenyl)-(2,4-dinitro-phenyl)-sulfide 
• 101724-25-8 3c-(2-chloro-phenylsulfanyl)-acrylic acid 
• 13420-53-6 2-((2-chlorophenyl)thio)benzoic acid 
• 65023-98-5 4-(2-chloro-phenylsulfanyl)-benzo[4,5]furo[3,2-d]pyrimidine 
• 51360-95-3 N-[2,2,2-Trichloro-1-(2-chloro-phenylsulfanyl)-ethyl]-formamide 
• 86026-62-2 1-{2-[2-(2-Chloro-phenylsulfanyl)-ethyl]-pyrrolidin-1-yl}-ethanone 
• 115368-23-5 N-[2-(2-Chloro-phenylsulfanyl)-ethyl]-N-methyl-acetamide 
• 17733-22-1 2-chlorothioanisole 
• 141358-05-6 3-(2-chlorophenylthio)benzoic acid 
• 20200-92-4 2-Chlor-4'-hydroxy-diphenyl-sulfid 
• 99585-16-7 3-[(2-chlorophenyl)thio]propanoic acid 
• 714243-39-7 3-(2-chloro-phenylsulfanyl)-6-methanesulfonyl-1H-indole-2-carboxylic acid methyl ester 

Relevant articles and documents

The aromatic thiol compound (by machine translation)

[A] at a high rate, and, high purity aromatic thiol compound method. [Solution] the presence of metal sulfide, with a compound represented by formula (1), by a vapor phase reaction of hydrogen sulfide, (2) an aromatic thiol compound represented by the formula manufacturing method. (R are each independently, C1 a-4 alkyl group, a hydroxyl group, amino group, cyano group, nitro group, C1 a-2 alkoxy group or a halogen atom; n is an integer of 0 - 5; X is a halogen atom)[Drawing] no (by machine translation)

Oxidative Cleavage of S-Arylmercaptoacetic Acids by Sodium Perborate: Kinetic and Correlation Study

Kinetics of oxidation of twenty six S-arylmercaptoacetic acids (SAMA) (I) by sodium perborate (PB) have been studied in acid medium.The product of oxidation is the corresponding thiophenol.The rate data of meta- and para-substituted acids have been correlated with DSP equations.While the para-compounds correlate well with ?I and ?0R values, the meta-compounds correlate well with ?I and ?-R values.The reaction constants are negative and of smaller magnitudes.Further, the ortho-substituted acids show a good correlation with a triparametric equation involving Taft's ?I and ?0R and Charton's steric parameter ν.There is a considerable steric contribution to the total ortho-substituent effect.Based on these observations, mechanism involving the formation of protonated arylsulfinylacetic acid intermediate, followed by an intramolecular rearrangement leading to the product thiophenol has been proposed.

S-Aryl(tetramethyl)isothiouronium salts as potential antimicrobial agents, II

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