5-(3-Benzoyl-thioureido)-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-imidazole-4-carboxylic acid amide

Base Information

Chemical Name:5-(3-Benzoyl-thioureido)-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-imidazole-4-carboxylic acid amide
CAS No.:112156-61-3
Molecular Formula:C₁₇H₁₉N₅O₆S
Molecular Weight:421.434
Hs Code.:

Synonyms:5-(3-Benzoyl-thioureido)-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-imidazole-4-carboxylic acid amide

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Chemical Property of 5-(3-Benzoyl-thioureido)-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-imidazole-4-carboxylic acid amide

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Technology Process of 5-(3-Benzoyl-thioureido)-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-imidazole-4-carboxylic acid amide

There total 1 articles about 5-(3-Benzoyl-thioureido)-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-imidazole-4-carboxylic acid amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2627-69-2
AICA riboside

: 532-55-8
Benzoyl isothiocyanate

: 112156-61-3
5-(3-Benzoyl-thioureido)-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-imidazole-4-carboxylic acid amide

Guidance literature:: In N,N-dimethyl-formamide; for 3h; Ambient temperature;
DOI:10.1016/S0040-4039(00)96067-2

Reference yield:

: 112156-61-3
5-(3-Benzoyl-thioureido)-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-imidazole-4-carboxylic acid amide

: 118-00-3
G

Guidance literature:: Multi-step reaction with 2 steps

1: MeI, NaOH

2: NH₃ / dimethylsulfoxide / 240 h / 100 °C

With sodium hydroxide; ammonia; methyl iodide; In dimethyl sulfoxide;
DOI:10.1039/c39860000901

Reference yield:

: 112156-61-3
5-(3-Benzoyl-thioureido)-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-imidazole-4-carboxylic acid amide

: 1-Benzoyl-3-[5-cyano-3-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-3H-imidazol-4-yl]-thiourea

Guidance literature:: With dicyclohexyl-carbodiimide; In N,N-dimethyl-formamide; for 24h; Ambient temperature;
DOI:10.1016/S0040-4039(00)96067-2