C₄₂H₄₆O₅Si

Base Information

• Chemical Name: C₄₂H₄₆O₅Si
• CAS No.: 1131849-75-6
• Molecular Formula: C₄₂H₄₆O₅Si
• Molecular Weight: 658.91
• Mol file: 1131849-75-6.mol

Synonyms:C₄₂H₄₆O₅Si

Chemical Property of C₄₂H₄₆O₅Si

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₂H₄₆O₅Si

There total 8 articles about C₄₂H₄₆O₅Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

C42H46O4Si (1131849-65-4) → C42H46O5Si (1131849-75-6)

Guidance literature:

With (5S,8R,9R)-2,2-dimethyl-10-oxo-1,3,6-trioxaspiro[4.5]decane-8,9-diyl diacetate; potassium peroxomonosulfate; tetra(n-butyl)ammonium hydrogensulfate; potassium carbonate; In dimethyl methyl ether; acetonitrile; at 0 ℃; for 0.416667h; pH=9.18; optical yield given as %ee; enantioselective reaction; aq. phosphate buffer;

DOI:10.1055/s-0028-1087371

Reference yield:

C42H46O4Si (1131849-72-3) → C42H46O5Si (1131849-75-6)

Guidance literature:

Multi-step reaction with 2 steps

1: iodine / chloroform / 25 h / 20 °C / Inert atmosphere

2: Oxone; potassium carbonate; tetra(n-butyl)ammonium hydrogensulfate; (5S,8R,9R)-2,2-dimethyl-10-oxo-1,3,6-trioxaspiro[4.5]decane-8,9-diyl diacetate / acetonitrile; aq. phosphate buffer / 0.42 h / 0 °C / pH 9.18

With (5S,8R,9R)-2,2-dimethyl-10-oxo-1,3,6-trioxaspiro[4.5]decane-8,9-diyl diacetate; Oxone; iodine; tetra(n-butyl)ammonium hydrogensulfate; potassium carbonate; In aq. phosphate buffer; chloroform; acetonitrile;

DOI:10.3987/COM-15-S(T)25

Reference yield:

C35H30N4O3S → C42H46O5Si (1131849-75-6)

Guidance literature:

Multi-step reaction with 4 steps

1.1: ammonium molybdate

2.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere

2.2: 0 - 20 °C / Inert atmosphere

3.1: iodine / chloroform / 25 h / 20 °C / Inert atmosphere

4.1: Oxone; potassium carbonate; tetra(n-butyl)ammonium hydrogensulfate; (5S,8R,9R)-2,2-dimethyl-10-oxo-1,3,6-trioxaspiro[4.5]decane-8,9-diyl diacetate / acetonitrile; aq. phosphate buffer / 0.42 h / 0 °C / pH 9.18

With (5S,8R,9R)-2,2-dimethyl-10-oxo-1,3,6-trioxaspiro[4.5]decane-8,9-diyl diacetate; Oxone; ammonium molybdate; iodine; tetra(n-butyl)ammonium hydrogensulfate; potassium carbonate; lithium hexamethyldisilazane; In tetrahydrofuran; aq. phosphate buffer; chloroform; acetonitrile; 2.1: |Julia-Kocienski Olefination / 2.2: |Julia-Kocienski Olefination;

DOI:10.3987/COM-15-S(T)25

upstream raw materials:

C₄₂H₄₆O₄Si

2-(2-((tert-butyldimethylsilyl)oxy)phenyl)acetaldehyde

C₃₅H₃₀N₄O₅S

C₄₂H₄₆O₄Si

Downstream raw materials:

C₃₆H₃₂O₅

C₃₆H₃₂O₅