(Z)-4-chloro-6-{(2R,4R,5S)-4-[(3,4-dimethoxybenzyl)oxy]-5-[(R)-2,2-dimethyl-1,3-dioxolan-4-yl]tetrahydrofuran-2-yl}hex-3-en-1-ol

Base Information

• Chemical Name: (Z)-4-chloro-6-{(2R,4R,5S)-4-[(3,4-dimethoxybenzyl)oxy]-5-[(R)-2,2-dimethyl-1,3-dioxolan-4-yl]tetrahydrofuran-2-yl}hex-3-en-1-ol
• CAS No.: 1023301-38-3
• Molecular Formula: C₂₄H₃₅ClO₇
• Molecular Weight: 470.991

Synonyms:(Z)-4-chloro-6-{(2R,4R,5S)-4-[(3,4-dimethoxybenzyl)oxy]-5-[(R)-2,2-dimethyl-1,3-dioxolan-4-yl]tetrahydrofuran-2-yl}hex-3-en-1-ol

Chemical Property of (Z)-4-chloro-6-{(2R,4R,5S)-4-[(3,4-dimethoxybenzyl)oxy]-5-[(R)-2,2-dimethyl-1,3-dioxolan-4-yl]tetrahydrofuran-2-yl}hex-3-en-1-ol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (Z)-4-chloro-6-{(2R,4R,5S)-4-[(3,4-dimethoxybenzyl)oxy]-5-[(R)-2,2-dimethyl-1,3-dioxolan-4-yl]tetrahydrofuran-2-yl}hex-3-en-1-ol

There total 5 articles about (Z)-4-chloro-6-{(2R,4R,5S)-4-[(3,4-dimethoxybenzyl)oxy]-5-[(R)-2,2-dimethyl-1,3-dioxolan-4-yl]tetrahydrofuran-2-yl}hex-3-en-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

tert-butyl[((Z)-4-chloro-6-{(2R,4R,5S)-4-[(3,4-dimethoxybenzyl)oxy]-5-[(R)-2,2-dimethyl-1,3-dioxolan-4-yl]tetrahydrofuran-2-yl}hex-3-en-1-yl)oxy]dimethylsilane → (Z)-4-chloro-6-{(2R,4R,5S)-4-[(3,4-dimethoxybenzyl)oxy]-5-[(R)-2,2-dimethyl-1,3-dioxolan-4-yl]tetrahydrofuran-2-yl}hex-3-en-1-ol (1023301-38-3)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 0 - 20 ℃; for 2h; Inert atmosphere;

DOI:10.1055/s-0036-1588169

Reference yield:

C21H31ClO7 + acetone (67-64-1) → (Z)-4-chloro-6-{(2R,4R,5S)-4-[(3,4-dimethoxybenzyl)oxy]-5-[(R)-2,2-dimethyl-1,3-dioxolan-4-yl]tetrahydrofuran-2-yl}hex-3-en-1-ol (1023301-38-3)

Guidance literature:

With pyridinium p-toluenesulfonate; at 20 ℃; for 23h; stereoselective reaction;

DOI:10.1021/ol800554f

Reference yield:

C21H31ClO7 (1023301-72-5) + acetone (67-64-1) → (Z)-4-chloro-6-{(2R,4R,5S)-4-[(3,4-dimethoxybenzyl)oxy]-5-[(R)-2,2-dimethyl-1,3-dioxolan-4-yl]tetrahydrofuran-2-yl}hex-3-en-1-ol (1023301-38-3)

Guidance literature:

With pyridinium p-toluenesulfonate; at 0 - 20 ℃;

DOI:10.1021/jo802806z

upstream raw materials:

acetone

C₂₁H₃₁ClO₇

C₂₀H₂₈O₆

Downstream raw materials:

C₂₄H₃₃ClO₇

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1023301-38-3 (Z)-4-chloro-6-{(2R,4R,5S)-4-[(3,4-dimethoxybenzyl)oxy]-5-[(R)-2,2-dimethyl-1,3-dioxolan-4-yl]tetrahydrofuran-2-yl}hex-3-en-1-ol

Send

Send

Metric Ton KG G Pound L ML

Send

Send