Technology Process of C28H27BrF4N4O5
There total 13 articles about C28H27BrF4N4O5 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium carbonate;
In
DMF (N,N-dimethyl-formamide);
at 60 ℃;
for 16h;
- Guidance literature:
-
Multi-step reaction with 7 steps
1: sodium azide / water; acetone / 3 h / Heating / reflux
2: hydrogen / palladium 10% on activated carbon / ethanol / 20 °C
3: dichloromethane / 20 °C
4: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran
5: boron tribromide / dichloromethane / -70 - 20 °C
6: triethylamine / dichloromethane / 24 h / 20 °C
7: potassium carbonate / DMF (N,N-dimethyl-formamide) / 16 h / 60 °C
With
sodium azide; di-isopropyl azodicarboxylate; hydrogen; boron tribromide; potassium carbonate; triethylamine; triphenylphosphine;
palladium 10% on activated carbon;
In
tetrahydrofuran; DMF (N,N-dimethyl-formamide); ethanol; dichloromethane; water; acetone;
- Guidance literature:
-
Multi-step reaction with 8 steps
1: sodium hydroxide; water; tetra-(n-butyl)ammonium iodide / dichloromethane / 168 h / 20 °C
2: sodium azide / water; acetone / 3 h / Heating / reflux
3: hydrogen / palladium 10% on activated carbon / ethanol / 20 °C
4: dichloromethane / 20 °C
5: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran
6: boron tribromide / dichloromethane / -70 - 20 °C
7: triethylamine / dichloromethane / 24 h / 20 °C
8: potassium carbonate / DMF (N,N-dimethyl-formamide) / 16 h / 60 °C
With
sodium hydroxide; sodium azide; di-isopropyl azodicarboxylate; water; hydrogen; boron tribromide; tetra-(n-butyl)ammonium iodide; potassium carbonate; triethylamine; triphenylphosphine;
palladium 10% on activated carbon;
In
tetrahydrofuran; DMF (N,N-dimethyl-formamide); ethanol; dichloromethane; water; acetone;