(αRS,4SR)-(2-tert-butyldimethylsilyl-1,2-thiazetidin-4-yl)(phenyl)methyl methanesulfonate 1,1-dioxide

Base Information

Chemical Name:(αRS,4SR)-(2-tert-butyldimethylsilyl-1,2-thiazetidin-4-yl)(phenyl)methyl methanesulfonate 1,1-dioxide
CAS No.:141462-79-5
Molecular Formula:C₁₆H₂₇NO₅S₂Si
Molecular Weight:405.612
Hs Code.:

Synonyms:(αRS,4SR)-(2-tert-butyldimethylsilyl-1,2-thiazetidin-4-yl)(phenyl)methyl methanesulfonate 1,1-dioxide

Suppliers and Price of (αRS,4SR)-(2-tert-butyldimethylsilyl-1,2-thiazetidin-4-yl)(phenyl)methyl methanesulfonate 1,1-dioxide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (αRS,4SR)-(2-tert-butyldimethylsilyl-1,2-thiazetidin-4-yl)(phenyl)methyl methanesulfonate 1,1-dioxide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (αRS,4SR)-(2-tert-butyldimethylsilyl-1,2-thiazetidin-4-yl)(phenyl)methyl methanesulfonate 1,1-dioxide

There total 1 articles about (αRS,4SR)-(2-tert-butyldimethylsilyl-1,2-thiazetidin-4-yl)(phenyl)methyl methanesulfonate 1,1-dioxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 130274-75-8,141462-77-3
(αR^*,4S^*)-2-(tert-butyldimethylsilyl)-4-(α-hydroxybenzyl)-1,2-thiazetidine 1,1-dioxide

: 124-63-0
methanesulfonyl chloride

: 141462-79-5
(αRS,4SR)-(2-tert-butyldimethylsilyl-1,2-thiazetidin-4-yl)(phenyl)methyl methanesulfonate 1,1-dioxide

Guidance literature:: With triethylamine; In dichloromethane; for 14h;

Reference yield: 81.0%

: 141462-79-5
(αRS,4SR)-(2-tert-butyldimethylsilyl-1,2-thiazetidin-4-yl)(phenyl)methyl methanesulfonate 1,1-dioxide

: 141462-83-1
(E)-4-benzylidene-2-(tert-butyldimethylsilyl)-1,2-thiazetidine 1,1-dioxide

Guidance literature:: With 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane; for 2h;

Reference yield:

: 141462-79-5
(αRS,4SR)-(2-tert-butyldimethylsilyl-1,2-thiazetidin-4-yl)(phenyl)methyl methanesulfonate 1,1-dioxide

: 134327-91-6
(E)-4-benzylidene-1,2-thiazetidine 1,1-dioxide

Guidance literature:: Multi-step reaction with 2 steps

1: 81 percent / 1,8-diazabicyclo<5.4.0>undec-7-ene (DBU) / CH₂Cl₂ / 2 h

2: 85 percent / 10percent tetrabutylammonium fluoride (TBAF) on silica gel (Fluka No_. 86876) / ethanol / 14 h

With tetrabutylammonium fluoride absorbed on silica gel; 1,8-diazabicyclo[5.4.0]undec-7-ene; In ethanol; dichloromethane;