1-ethyl-4-(4-(dimethylamino)phenyl)-6-methyl-2(1H)-pyrimidone

Base Information

• Chemical Name: 1-ethyl-4-(4-(dimethylamino)phenyl)-6-methyl-2(1H)-pyrimidone
• CAS No.: 1318072-04-6
• Molecular Formula: C₁₅H₁₉N₃O
• Molecular Weight: 257.335
• Mol file: 1318072-04-6.mol

Synonyms:1-ethyl-4-(4-(dimethylamino)phenyl)-6-methyl-2(1H)-pyrimidone

Chemical Property of 1-ethyl-4-(4-(dimethylamino)phenyl)-6-methyl-2(1H)-pyrimidone

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of 1-ethyl-4-(4-(dimethylamino)phenyl)-6-methyl-2(1H)-pyrimidone

There total 1 articles about 1-ethyl-4-(4-(dimethylamino)phenyl)-6-methyl-2(1H)-pyrimidone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 24.0%

N-Ethylurea (625-52-5) + 1-(4-N,N-dimethylaminophenyl)-1,3-butadione (20449-17-6) → 1-ethyl-6-(4-(dimethylamino)phenyl)-4-methyl-2(1H)-pyrimidone (1318072-05-7) + 1-ethyl-4-(4-(dimethylamino)phenyl)-6-methyl-2(1H)-pyrimidone (1318072-04-6)

Guidance literature:

With hydrogenchloride; In ethanol; water; at 80 ℃; for 8h;

DOI:10.1021/ol2014945

Reference yield:

1-ethyl-4-(4-(dimethylamino)phenyl)-6-methyl-2(1H)-pyrimidone (1318072-04-6) + trifluoroacetic acid (76-05-1) → C2HF3O2*C15H19N3O

Guidance literature:

In dichloromethane;

DOI:10.1021/ol2014945

upstream raw materials:

N-Ethylurea

1-(4-N,N-dimethylaminophenyl)-1,3-butadione