(R,E)-4-(((1R,2S)-2-acetoxy-1-(4-methoxyphenyl)-3-phenylpropyl)((S)-1,1-dimethoxy-3-phenylpropan-2-yl)amino)-1-phenylbut-2-enyl acetate

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Chemical Name:(R,E)-4-(((1R,2S)-2-acetoxy-1-(4-methoxyphenyl)-3-phenylpropyl)((S)-1,1-dimethoxy-3-phenylpropan-2-yl)amino)-1-phenylbut-2-enyl acetate
CAS No.:1256467-85-2
Molecular Formula:C₄₁H₄₇NO₇
Molecular Weight:665.827
Hs Code.:

Synonyms:(R,E)-4-(((1R,2S)-2-acetoxy-1-(4-methoxyphenyl)-3-phenylpropyl)((S)-1,1-dimethoxy-3-phenylpropan-2-yl)amino)-1-phenylbut-2-enyl acetate

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Chemical Property of (R,E)-4-(((1R,2S)-2-acetoxy-1-(4-methoxyphenyl)-3-phenylpropyl)((S)-1,1-dimethoxy-3-phenylpropan-2-yl)amino)-1-phenylbut-2-enyl acetate

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Technology Process of (R,E)-4-(((1R,2S)-2-acetoxy-1-(4-methoxyphenyl)-3-phenylpropyl)((S)-1,1-dimethoxy-3-phenylpropan-2-yl)amino)-1-phenylbut-2-enyl acetate

There total 1 articles about (R,E)-4-(((1R,2S)-2-acetoxy-1-(4-methoxyphenyl)-3-phenylpropyl)((S)-1,1-dimethoxy-3-phenylpropan-2-yl)amino)-1-phenylbut-2-enyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 1256467-62-5
(R,E)-4-(((S)-1,1-dimethoxy-3-phenylpropan-2-yl)((1R,2S)-2-hydroxy-1-(4-methoxyphenyl)-3-phenylpropyl)amino)-1-phenylbut-2-en-1-ol

: 108-24-7
acetic anhydride

: 1256467-85-2
(R,E)-4-(((1R,2S)-2-acetoxy-1-(4-methoxyphenyl)-3-phenylpropyl)((S)-1,1-dimethoxy-3-phenylpropan-2-yl)amino)-1-phenylbut-2-enyl acetate

Guidance literature:: With pyridine; dmap; at 20 ℃; Inert atmosphere;
DOI:10.1021/ol102266j

Reference yield: 78.0%

: 1256467-85-2
(R,E)-4-(((1R,2S)-2-acetoxy-1-(4-methoxyphenyl)-3-phenylpropyl)((S)-1,1-dimethoxy-3-phenylpropan-2-yl)amino)-1-phenylbut-2-enyl acetate

: 1256467-66-9
(S,E)-1-(((1R,2S)-2-acetoxy-1-(4-methoxyphenyl)-3-phenylpropyl)((S)-1,1-dimethoxy-3-phenylpropan-2-yl)amino)-4-phenylbut-3-en-2-yl acetate

Guidance literature:: With dichloro bis(acetonitrile) palladium(II); In dichloromethane; at 20 ℃; stereoselective reaction; Inert atmosphere;
DOI:10.1021/ol102266j