acetic acid-(3-chloro-pentyl ester)

Base Information

• Chemical Name: acetic acid-(3-chloro-pentyl ester)
• CAS No.: 49633-68-3
• Molecular Formula: C₇H₁₃ClO₂
• Molecular Weight: 164.632
• Mol file: 49633-68-3.mol

Synonyms:acetic acid-(3-chloro-pentyl ester)

Chemical Property of acetic acid-(3-chloro-pentyl ester)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of acetic acid-(3-chloro-pentyl ester)

There total 3 articles about acetic acid-(3-chloro-pentyl ester) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-pentyl acetate (628-63-7) → acetic acid-(3-chloro-pentyl ester) (49633-68-3) + 1-acetoxy-4-chloropentane (36978-15-1) + 5-chloropentyl acetate (20395-28-2)

Guidance literature:

With perchloric acid; 1-chloro-cis-2,6-dimethylpiperidine; In water; at 0 ℃; for 2h; Overall yield = 51 percent; Irradiation; Sealed tube; Inert atmosphere;

DOI:10.1002/anie.202100030

Reference yield:

1-pentyl acetate (628-63-7) → acetic acid-(3-chloro-pentyl ester) (49633-68-3) + 1-acetoxy-4-chloropentane (36978-15-1) + 5-chloropentyl acetate (20395-28-2) + Essigsaeure-<2-chlor-pentylester> (49633-67-2)

Guidance literature:

With N-chloropiperidine; 2,2'-azobis(isobutyronitrile); In trifluoroacetic acid; at 30 ℃; Product distribution; Rate constant; Irradiation; relative rate constants, position selectivity, substrate selectivity;

Reference yield:

1-pentyl acetate (628-63-7) → acetic acid-(3-chloro-pentyl ester) (49633-68-3) + 1-acetoxy-4-chloropentane (36978-15-1) + 5-chloropentyl acetate (20395-28-2) + Essigsaeure-(α-chlor-pentylester) (13398-06-6) + Essigsaeure-<2-chlor-pentylester> (49633-67-2)

Guidance literature:

With chlorine; In neat (no solvent); Product distribution; Ambient temperature; chlorine substitution on the alcoholic chain of aliphatic C₂-C₈ n-alkyl acetates, chloroacetates, dichloroacetates and trichloroacetates; formation of monochloro isomers;

upstream raw materials:

1-pentyl acetate

Refernces

• 1、 Quinn, Ryan K.,K?nst, Zef A.,Michalak, Sharon E.,Schmidt, Yvonne,Szklarski, Anne R.,Flores, Alex R.,Nam, Sangkil,Horne, David A.,Vanderwal, Christopher D.,Alexanian, Erik J.. "Site-Selective Aliphatic C-H Chlorination Using N-Chloroamides Enables a Synthesis of Chlorolissoclimide". supporting information. p. 696 - 702. Retrieved 2016/02/03.
• 2、 Korhonen, Ilpo O. O.. "Chlorination of Carboxylic Acid Derivatives. IX. Liquid Phase Chlorination of Aliphatic C2-C8 Alkyl Acetates. EI Mass Spectra of Monochlorinated Esters". . p. 39 - 46. Retrieved 2007/10/02.