N--N-(4-methoxybenzyl)glycine

Base Information

Chemical Name:N--N-(4-methoxybenzyl)glycine
CAS No.:130740-51-1
Molecular Formula:C₁₉H₁₇NO₅
Molecular Weight:339.348
Hs Code.:

N-<benzofuranyl-2(3H)>-N-(4-methoxybenzyl)glycine

Synonyms:N--N-(4-methoxybenzyl)glycine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N--N-(4-methoxybenzyl)glycine

Chemical Property:

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Technology Process of N--N-(4-methoxybenzyl)glycine

There total 6 articles about N--N-(4-methoxybenzyl)glycine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 41717-28-6
2-benzofuroyl chloride

: 130740-51-1
N--N-(4-methoxybenzyl)glycine

Guidance literature:: Multi-step reaction with 2 steps

1: NaHCO₃ / CH₂Cl₂; H₂O / 1 h / Ambient temperature

2: LiOH / ethanol / 24 h / Ambient temperature

With lithium hydroxide; sodium hydrogencarbonate; In ethanol; dichloromethane; water;
DOI:10.1021/ja00055a025

Reference yield:

: [(Benzofuran-2-carbonyl)-(4-methoxy-benzyl)-amino]-acetic acid ethyl ester

: 130740-51-1
N--N-(4-methoxybenzyl)glycine

Guidance literature:: With lithium hydroxide; In ethanol; for 24h; Yield given; Ambient temperature;
DOI:10.1016/S0040-4039(00)97605-6 DOI:10.1021/ja00055a025

Reference yield:

: 496-41-3
Benzofuran-2-carboxylic acid

: 130740-51-1
N--N-(4-methoxybenzyl)glycine

Guidance literature:: Multi-step reaction with 3 steps

1: SOCl₂ / benzene / 4 h / Heating

2: NaHCO₃ / CH₂Cl₂; H₂O / 1 h / Ambient temperature

3: LiOH / ethanol / 24 h / Ambient temperature

With lithium hydroxide; thionyl chloride; sodium hydrogencarbonate; In ethanol; dichloromethane; water; benzene;
DOI:10.1021/ja00055a025