1-[2-(2,4-dimethylphenyl)-2-oxoethyl]-3,5-dimethylpyridinium bromide

Base Information

• Chemical Name: 1-[2-(2,4-dimethylphenyl)-2-oxoethyl]-3,5-dimethylpyridinium bromide
• CAS No.: 1434567-21-1
• Molecular Formula: Br*C₁₇H₂₀NO
• Molecular Weight: 334.256
• Mol file: 1434567-21-1.mol

Synonyms:1-[2-(2,4-dimethylphenyl)-2-oxoethyl]-3,5-dimethylpyridinium bromide

Chemical Property of 1-[2-(2,4-dimethylphenyl)-2-oxoethyl]-3,5-dimethylpyridinium bromide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 1-[2-(2,4-dimethylphenyl)-2-oxoethyl]-3,5-dimethylpyridinium bromide

There total 1 articles about 1-[2-(2,4-dimethylphenyl)-2-oxoethyl]-3,5-dimethylpyridinium bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

3,5-Lutidine (591-22-0) + 2-bromo-1-(2,4-dimethylphenyl)ethanone (26346-85-0) → 1-[2-(2,4-dimethylphenyl)-2-oxoethyl]-3,5-dimethylpyridinium bromide (1434567-21-1)

Guidance literature:

In acetone; Reflux;

DOI:10.1016/j.tet.2013.03.098

Reference yield: 75.0%

1-[2-(2,4-dimethylphenyl)-2-oxoethyl]-3,5-dimethylpyridinium bromide (1434567-21-1) + E-1,2-dichloro-1,2-di(propylsulfonyl)ethene (118524-81-5) → [6,8-dimethyl-1,2-bis(propylsulfonyl)-3-indolizinyl](2,4-dimethylphenyl)methanone (903810-56-0)

Guidance literature:

1-[2-(2,4-dimethylphenyl)-2-oxoethyl]-3,5-dimethylpyridinium bromide; With triethylamine; In chloroform;

E-1,2-dichloro-1,2-di(propylsulfonyl)ethene; In chloroform; at 50 ℃; for 0.666667h; regioselective reaction;

DOI:10.1016/j.tet.2013.03.098

Reference yield: 9.0%

1-[2-(2,4-dimethylphenyl)-2-oxoethyl]-3,5-dimethylpyridinium bromide (1434567-21-1) + E-1,2-dichloro-1,2-di(propylsulfonyl)ethene (118524-81-5) → 1-[2-(2,4-dimethylphenyl)-4,5-bis(propylsulfonyl)-3-furyl]-3,5-dimethylpyridinium bromide (1434568-50-9) + [6,8-dimethyl-1,2-bis(propylsulfonyl)-3-indolizinyl](2,4-dimethylphenyl)methanone (903810-56-0)

Guidance literature:

1-[2-(2,4-dimethylphenyl)-2-oxoethyl]-3,5-dimethylpyridinium bromide; With triethylamine; In ethanol;

E-1,2-dichloro-1,2-di(propylsulfonyl)ethene; In ethanol; at 50 ℃; for 0.666667h;

With hydrogen bromide; In acetic acid; at 50 - 60 ℃;

DOI:10.1016/j.tet.2013.03.098

upstream raw materials:

3,5-Lutidine

2-bromo-1-(2,4-dimethylphenyl)ethanone

Downstream raw materials:

[6,8-dimethyl-1,2-bis(propylsulfonyl)-3-indolizinyl](2,4-dimethylphenyl)methanone

1-[2-(2,4-dimethylphenyl)-4,5-bis(propylsulfonyl)-3-furyl]-3,5-dimethylpyridinium bromide