26346-85-0

Usage

Uses

Used in Pharmaceutical Industry:
2-BROMO-1-(2,4-DIMETHYLPHENYL)ETHAN-1-ONE is used as a key intermediate for the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents. Its unique chemical structure allows for the creation of molecules with specific medicinal properties, enhancing the range of treatments available for various health conditions.
Used in Agrochemical Industry:
In the agrochemical sector, 2-BROMO-1-(2,4-DIMETHYLPHENYL)ETHAN-1-ONE serves as a versatile intermediate in the production of agrochemicals. It plays a crucial role in the synthesis of pesticides, herbicides, and other agricultural chemicals, helping to improve crop yields and protect plants from pests and diseases.
Used in Fine Chemicals Production:
2-BROMO-1-(2,4-DIMETHYLPHENYL)ETHAN-1-ONE is utilized as an intermediate in the manufacture of fine chemicals, which are high-purity chemicals used in various applications such as fragrances, flavors, dyes, and coatings. Its unique properties enable the production of specialty chemicals with specific characteristics, catering to the diverse needs of various industries.
Used in Industrial Chemistry:
2-BROMO-1-(2,4-DIMETHYLPHENYL)ETHAN-1-ONE also finds applications in industrial chemistry, where it is employed in the synthesis of various organic compounds and materials. Its unique chemical properties make it a valuable component in the development of new industrial products and processes, contributing to advancements in various sectors.

InChI:InChI=1/C10H11BrO/c1-7-3-4-9(8(2)5-7)10(12)6-11/h3-5H,6H2,1-2H3

Upstream product

• 861555-96-6 1-(bromoethynyl)-2,4-dimethylbenzene 
• 598-21-0 2-Bromoacetyl bromide 
• 108-38-3 m-xylene 
• 7664-93-9 sulfuric acid 
• 64-19-7 acetic acid 
• 89-74-7 2,4-dimethylacetophenone. 

Downstream Products

• 99842-63-4 4-(2,4-dimethyl-phenyl)-3H-thiazol-2-one 
• 101446-58-6 (5-chloro-benzofuran-2-yl)-(2,4-dimethyl-phenyl)-ketone 
• 802270-16-2 1-(2,4-dimethyl-phenyl)-2-(2-imino-thiazolidin-3-yl)-ethanone 
• 497957-92-3 1,4-bis-(2,4-dimethyl-phenyl)-butane-1,4-dione 
• 103793-29-9 1-methyl-3-[2-(2,4-dimethylphenyl)-2-oxoethyl]-1H-imidazolium bromide 
• 1219623-36-5 2,2'-(1,4-phenylene)bis[5-(2,4-dimethylphenyl)-1H-imidazole] 
• 312743-68-3 C₁₆H₁₄N₂OS₂ 
• 1421376-26-2 N-(4-(2,4-dimethylphenyl)-3-methylthiazol-2(3H)-ylidene)thiophene-2-carboxamide 
• 1421376-31-9 N-(4-(2,4-dimethylphenyl)-3-methylthiazol-2(3H)-ylidene)benzamide 
• 6097-20-7 1-(2,4-dimethyl-phenyl)-2-thiocyanato-ethanone 

Relevant academic research and scientific papers

Discovery of novel potent GPR40 agonists containing imidazo[1,2-a]pyridine core as antidiabetic agents

Free fatty acid receptor 1 (FFA1 or GPR40) has been studied for many years as a target for the treatment of type 2 diabetes mellitus. In order to increase potency and reduce hepatotoxicity, a series of novel compounds containing imidazo[1,2-a]pyridine sca

Organocatalytic Enantioselective Selenosulfonylation of a C-C Double Bond to Form Two Stereogenic Centers in an Aqueous Medium

Organocatalytic selenosulfonylation of the C-C double bond of α,β-unsaturated ketones to construct two contiguous stereogenic centers in an aqueous medium was described. A series of α-selenyl and β-sulfonyl ketones with various functional groups were synthesized in good yields and enantioselectivities with saturated NaCl solution as the solvent. In addition, this protocol had been successfully scaled up to a decagram scale via a simple workup procedure.

Synthesis and antimicrobial activity evaluation of new dithiocarbamate derivatives bearing thiazole/benzothiazole rings

The synthesis of 2-(substituted phenyl)-2-oxoethyl 4-(pyrimidin-2-yl)piperazin-1-carbodithiodate (A1-A24) derivatives and 2-(4-substituted thiazol-2-ylamino)-2-oxoethyl 4-(pyrimidin-2-yl)piperazin-1-carbodithiodate (B1-B14) derivatives was undertaken starting from the potassium salt of 4-(2-pyrimidinyl)piperazine dithiocarbamate. The structures of the obtained compounds were elucidated by1H NMR,13C NMR, MS spectral data, and elemental analysis. The antimicrobial activity of the thirty eight newly synthesized compounds were tested against 12 microorganism strains using the microdilution technique. Compounds 2-(4-ethoxycarbonylthiazol-2-ylamino)-2-oxoethyl 4-(pyrimidin-2-yl)piperazin-1-carbodithiodate (B12), 2-(3-fluorophenyl)-2-oxoethyl 4-(pyrimidin-2-yl)piperazin-1-carbodithiodate (A18) and 2-(3,4-difluorophenyl)-2-oxoethyl 4-(pyrimidin-2-yl)piperazin-1-carbodithiodate (A21) were determined to possess high antimicrobial activity.

Azabicyclo derivative and preparation method therefor and application thereof

The invention relates to an azabicyclo derivative and a preparation method therefor and an application thereof. Specifically, the invention discloses a compound with a structure represented by a formula (A) or salts acceptable in pesticide science thereof, wherein the compound represented by the formula (A) is as shown in the description. The compound has an excellent killing effect on nematodes.

Synthesis and biological evaluation of N-(4-phenylthiazol-2-yl)cinnamamide derivatives as novel potential anti-tumor agents

In this study, a series of novel N-(4-phenylthiazol-2-yl)cinnamamide derivatives (7a-8n) were synthesized and evaluated for their anti-proliferative activities in vitro by MTT assay and a possible antitumor mechanism was also explored. SAR analysis showed that steric effects played an important role on the anti-tumor activity. The most potent analogue 8f showed excellent inhibitions on the K562, Bel7402, A549 and Jurkat cells ranging from sub-micromolar to nanomolar concentration. Compound 8f inhibited Jurkat cells with an IC50 value of 0.035 μM with no apparent toxicity in different non-cancerous cells. Furthermore, it was suggested that the possible mechanism of 8f might be associated with inducing cancer cell apoptosis following flow cytometer analysis and Hoechst 33358 staining assays.

SUBSTITUTED THIAZOLE DERIVATIVES BEARING 3-PYRIDYL GROUPS, PROCESS FOR PREPARING THE SAME AND USE THEREOF

The present invention provides a pharmaceutical composition having a steroid C17,20-lyase inhibitory activity, which is useful as a prophylactic or therapeutic agent of prostatism, tumor such as breast cancer and the like, more particularly, a steroid C17,20-lyase inhibitor containing a compound represented by the formula: wherein A1 is an aromatic hydrocarbon group optionally having substituents or a heterocyclic group optionally having substituents, one of A2 and A3 is a hydrogen atom, a halogen atom, a C1-4 aliphatic hydrocarbon group optionally having substituents or an optionally esterified carboxyl group, the other of A2 and A3 is an aromatic hydrocarbon group optionally having substituents or a heterocyclic group optionally having substituents, and at least one of A1, A2 and A3 is a 3-pyridyl group optionally having substituents, or a salt thereof or a prodrug thereof.

Antifungal amine derivatives and processing for producing the same

Novel amine derivatives having an excellent antimycotic effect represented by general formula (1) below and salts thereof are provided. [in the formula (1, R1represents a C1-5alkyl group which may be halogenated, R2represents 4-(1,1-dimethylalkyl)benzyl group, 4-(1-methyl-phenylethyl)benzyl group, 1-or 2-naphthylmethyl group, or a hydrocarbon group having 3,3-dimethyl-1-butynyl group or a phenyl group at its terminal and 1 to 3 double bonds; R3represents oxygen atom or a methylene group which may be substituted by a C1-4alkyl group; and R4represents 1-or 2 naphthyl group or a phenyl group which may be substituted.