Technology Process of 10-butyl-7-(2-phenylethynyl)-10H-phenothiazine-3-carbaldehyde
There total 3 articles about 10-butyl-7-(2-phenylethynyl)-10H-phenothiazine-3-carbaldehyde which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
copper(l) iodide; palladium diacetate; triethylamine; triphenylphosphine;
In
tetrahydrofuran;
for 6h;
Inert atmosphere;
Reflux;
DOI:10.1007/s10895-010-0791-1
- Guidance literature:
-
Multi-step reaction with 4 steps
1: cetyltrimethylammonim bromide; sodium hydroxide / acetone / 6 h / Reflux
2: trichlorophosphate / chloroform / 16 h / Reflux
3: bromine; acetic acid / 48 h / 20 °C
4: copper(l) iodide; palladium diacetate; triethylamine; triphenylphosphine / tetrahydrofuran / 6 h / Inert atmosphere; Reflux
With
copper(l) iodide; bromine; cetyltrimethylammonim bromide; palladium diacetate; acetic acid; triethylamine; triphenylphosphine; sodium hydroxide; trichlorophosphate;
In
tetrahydrofuran; chloroform; acetone;
4: Sonogashira coupling;
DOI:10.1007/s10895-010-0791-1
- Guidance literature:
-
Multi-step reaction with 2 steps
1: bromine; acetic acid / 48 h / 20 °C
2: copper(l) iodide; palladium diacetate; triethylamine; triphenylphosphine / tetrahydrofuran / 6 h / Inert atmosphere; Reflux
With
copper(l) iodide; bromine; palladium diacetate; acetic acid; triethylamine; triphenylphosphine;
In
tetrahydrofuran;
2: Sonogashira coupling;
DOI:10.1007/s10895-010-0791-1
