(R)-(-)-Phenylsuccinic acid

Base Information

Chemical Name:(R)-(-)-Phenylsuccinic acid
CAS No.:46292-93-7
Molecular Formula:C10H10O4
Molecular Weight:194.187
Hs Code.:2917399090
DSSTox Substance ID:DTXSID70352942
Nikkaji Number:J84.177C
Wikidata:Q27460426
Mol file:46292-93-7.mol

Synonyms:46292-93-7;(R)-(-)-Phenylsuccinic acid;(R)-2-Phenylsuccinic acid;(2R)-2-phenylbutanedioic acid;(R)-2-Phenyl succinic acid;Butanedioic acid, phenyl-, (2R)-;(2R)-2-phenylbutanedioic acid >99% ee;MFCD00065930;(R)-2-PHENYLSUCCINICACID;r-phenylsuccinic acid;SCHEMBL377609;(R)-2-Phenylbutanedioic acid;(R)-(')-Phenylsuccinic acid;DTXSID70352942;CHEBI:151044;WBA29293;AKOS006239803;SS-4842;BP-12920;CS-0141922;A827021;A1-00043;Q27460426;(R)-(-)-Phenylsuccinic acid, >=96.0% (sum of enantiomers, HPLC)

Suppliers and Price of (R)-(-)-Phenylsuccinic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(R)-(?)-Phenylsuccinic acid
1g
$ 185.00

TRC
(R)-(?)-Phenylsuccinic acid
250mg
$ 100.00

SynQuest Laboratories
(2R)-2-Phenylbutanedioic acid 99 ee%
500 mg
$ 128.00

SynQuest Laboratories
(2R)-2-Phenylbutanedioic acid 99 ee%
1 g
$ 176.00

Sigma-Aldrich
(R)-(?)-Phenylsuccinic acid ≥96.0% (sum of enantiomers, HPLC)
1g
$ 131.00

Crysdot
(R)-2-Phenylsuccinicacid 97%
10g
$ 673.00

Crysdot
(R)-2-Phenylsuccinicacid 97%
25g
$ 1239.00

Crysdot
(R)-2-Phenylsuccinicacid 97%
5g
$ 354.00

Apolloscientific
(2R)-2-Phenylbutanedioicacid >99%e.e.
1g
$ 160.00

Apolloscientific
(2R)-2-Phenylbutanedioicacid >99%e.e.
500mg
$ 116.00

Total 27 raw suppliers

Chemical Property of (R)-(-)-Phenylsuccinic acid

Chemical Property:

Appearance/Colour:almost white fine powder
Vapor Pressure:0.000306mmHg at 25°C
Melting Point:173-176 °C
Refractive Index:1.577
Boiling Point:307.8 °C at 760mmHg
PKA:3.60±0.10(Predicted)
Flash Point:154.2 °C
PSA：74.60000
Density:1.336g/cm³
LogP:1.32950
Storage Temp.:Sealed in dry,Room Temperature
Solubility.:Acetone (Slightly), Methanol (Slightly)
XLogP3:0.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:194.05790880
Heavy Atom Count:14
Complexity:218

Purity/Quality:

97% ^*data from raw suppliers

(R)-(?)-Phenylsuccinic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 22-24/25

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(CC(=O)O)C(=O)O
Isomeric SMILES:C1=CC=C(C=C1)[C@@H](CC(=O)O)C(=O)O
Uses (R)-Phenylsuccinic Acid is an intermediate used in the preparation of optically active succinic acid derivatives used as hypoglycemic agents.

Technology Process of (R)-(-)-Phenylsuccinic acid

There total 3 articles about (R)-(-)-Phenylsuccinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 635-51-8,10424-29-0
2-phenylsuccinic acid

: 4036-30-0
(S)-2-phenylsuccinic acid

: 46292-93-7
R-(+)-phenylsuccinic acid

Guidance literature:: With sodium hydroxide; thionyl chloride; brucine; Product distribution; multistep reaction; 2.) 100 deg C; the ratio of the racemization;
DOI:10.1002/hlca.19820650135