2,3-Dichlorobenzylamine

Base Information

• Chemical Name: 2,3-Dichlorobenzylamine
• CAS No.: 39226-95-4
• Molecular Formula: C7H7Cl2N
• Molecular Weight: 176.045
• Hs Code.: 29214990
• Mol file: 39226-95-4.mol

Synonyms:Benzylamine,2,3-dichloro- (6CI);(2,3-Dichlorophenyl)methanamine;[(2,3-Dichlorophenyl)methyl]amine;

Chemical Property of 2,3-Dichlorobenzylamine

Chemical Property:

• Appearance/Colour: clear colorless to light yellow liquid
• Vapor Pressure: 0.0178mmHg at 25°C
• Refractive Index: n20/D 1.583(lit.)
• Boiling Point: 253.861 °C at 760 mmHg
• Flash Point: 107.332 °C
• PSA: 26.02000
• Density: 1.32 g/cm³
• LogP: 3.15240
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Sensitive.: Air Sensitive

Purity/Quality:

99% ^*data from raw suppliers

2,3-Dichlorobenzylamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,3-Dichlorobenzylamine

There total 3 articles about 2,3-Dichlorobenzylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

→ (2,3-dichlorophenyl)methanamine (39226-95-4)

Guidance literature:

With water; potassium hydroxide; In ethanol; at 90 ℃; for 10h;

Reference yield: 75.0%

2,3-dichlorobenzonitrile (6574-97-6) → (2,3-dichlorophenyl)methanamine (39226-95-4)

Guidance literature:

With indium(III) chloride; sodium tetrahydroborate; In tetrahydrofuran; at 25 ℃; for 4h; Inert atmosphere;

DOI:10.1021/jo201809a

Reference yield:

2,3-dichlorotoluene (32768-54-0) → (2,3-dichlorophenyl)methanamine (39226-95-4)

Guidance literature:

Multistep reaction; (i) Br₂, (heating), (ii) hexamethylenetetramine;

upstream raw materials:

2,3-dichlorotoluene

2,3-dichlorobenzonitrile

Downstream raw materials:

1-(2,3-Dichloro-benzyl)-4-oxo-7-pyridin-4-yl-1,4-dihydro-quinoline-3-carboxylic acid ethyl ester

N-(2,3-dichlorobenzyl)-3-nitrobenzenesulfonamide

3-(2,3-dichlorobenzyl)-1-(2-hydroxyethyl)-1-methylurea