Technology Process of 4-Amino-1-(4-methoxy-phenyl)-butan-1-one
There total 1 articles about 4-Amino-1-(4-methoxy-phenyl)-butan-1-one which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
trifluorormethanesulfonic acid;
at 80 ℃;
for 1h;
Cooling with ice;
- Guidance literature:
-
With
palladium 10% on activated carbon; hydrogen;
In
tetrahydrofuran; water;
at 50 ℃;
for 24h;
under 3102.97 Torr;
Inert atmosphere;
- Guidance literature:
-
Multi-step reaction with 7 steps
1: hydrogen; palladium 10% on activated carbon / water; tetrahydrofuran / 24 h / 50 °C / 3102.97 Torr / Inert atmosphere
2: hydrogen bromide / water / 3 h / 20 °C / Reflux
3: sodium hydrogencarbonate / water; 1,4-dioxane / 0 - 20 °C
4: potassium iodide; potassium carbonate / acetonitrile / 10 h / Inert atmosphere; Reflux
5: triethylamine / toluene / 6 h / Reflux; Inert atmosphere
6: hydrogenchloride / 1,4-dioxane / 0.5 h / 20 °C
7: N-ethyl-N,N-diisopropylamine / ethanol / 3 h / Reflux
With
hydrogenchloride; palladium 10% on activated carbon; hydrogen bromide; hydrogen; sodium hydrogencarbonate; potassium carbonate; triethylamine; N-ethyl-N,N-diisopropylamine; potassium iodide;
In
tetrahydrofuran; 1,4-dioxane; ethanol; water; toluene; acetonitrile;
