2,6-di-tert-butyl-4-(3,5-difluorobenzylidene)cyclohexa-2,5-dienone

Base Information

• Chemical Name: 2,6-di-tert-butyl-4-(3,5-difluorobenzylidene)cyclohexa-2,5-dienone
• CAS No.: 1176861-69-0
• Molecular Formula: C₂₁H₂₄F₂O
• Molecular Weight: 330.418
• Mol file: 1176861-69-0.mol

Synonyms:2,6-di-tert-butyl-4-(3,5-difluorobenzylidene)cyclohexa-2,5-dienone

Chemical Property of 2,6-di-tert-butyl-4-(3,5-difluorobenzylidene)cyclohexa-2,5-dienone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,6-di-tert-butyl-4-(3,5-difluorobenzylidene)cyclohexa-2,5-dienone

There total 1 articles about 2,6-di-tert-butyl-4-(3,5-difluorobenzylidene)cyclohexa-2,5-dienone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

2,6-di-tert-butylphenol (128-39-2) + 3,5-difluorobenzaldehyde (32085-88-4) → 2,6-di-tert-butyl-4-(3,5-difluorobenzylidene)cyclohexa-2,5-dienone (1176861-69-0)

Guidance literature:

2,6-di-tert-butylphenol; 3,5-difluorobenzaldehyde; In toluene; for 4h; Dean-Stark; Reflux;

With acetic anhydride; In toluene; for 0.25h; Dean-Stark;

DOI:10.1039/d0ob00039f

Reference yield: 87.0%

2,6-di-tert-butyl-4-(3,5-difluorobenzylidene)cyclohexa-2,5-dienone (1176861-69-0) + C12H21NO5 → C33H45F2NO6

Guidance literature:

With scandium tris(trifluoromethanesulfonate); In acetonitrile; at 20 ℃; chemoselective reaction;

DOI:10.1039/d0ob00039f

Reference yield: 82.0%

2,6-di-tert-butyl-4-(3,5-difluorobenzylidene)cyclohexa-2,5-dienone (1176861-69-0) + 2,3,4,6-tetra-O-acetyl-α-D-mannopyranosylamine (1453084-80-4) → C35H45F2NO10

Guidance literature:

With scandium tris(trifluoromethanesulfonate); In acetonitrile; at 20 ℃; chemoselective reaction;

DOI:10.1039/d0ob00039f

upstream raw materials:

2,6-di-tert-butylphenol

3,5-difluorobenzaldehyde