bis(4,4-dimethyl-2-(1-hydroxy-1-methylethyl)-4,5-dihydrooxazole)phenylphosphonite

Base Information

• Chemical Name: bis(4,4-dimethyl-2-(1-hydroxy-1-methylethyl)-4,5-dihydrooxazole)phenylphosphonite
• CAS No.: 286407-90-7
• Molecular Formula: C₂₂H₃₃N₂O₄P
• Molecular Weight: 420.489
• Mol file: 286407-90-7.mol

Synonyms:bis(4,4-dimethyl-2-(1-hydroxy-1-methylethyl)-4,5-dihydrooxazole)phenylphosphonite

Chemical Property of bis(4,4-dimethyl-2-(1-hydroxy-1-methylethyl)-4,5-dihydrooxazole)phenylphosphonite

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of bis(4,4-dimethyl-2-(1-hydroxy-1-methylethyl)-4,5-dihydrooxazole)phenylphosphonite

There total 1 articles about bis(4,4-dimethyl-2-(1-hydroxy-1-methylethyl)-4,5-dihydrooxazole)phenylphosphonite which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4,4'-dimethyl-2-(1-hydroxy-1-methylethyl)-4,5-dihydrooxazole (86354-07-6) + Dichlorophenylphosphine (644-97-3) → bis(4,4-dimethyl-2-(1-hydroxy-1-methylethyl)-4,5-dihydrooxazole)phenylphosphonite (286407-90-7)

Guidance literature:

With triethylamine; In tetrahydrofuran; at -78 ℃;

DOI:10.1039/b401792g

Reference yield: 97.0%

cobalt(II) chloride (7646-79-9,14543-09-0,16413-89-1) + bis(4,4-dimethyl-2-(1-hydroxy-1-methylethyl)-4,5-dihydrooxazole)phenylphosphonite (286407-90-7) → [CoCl2(bis(oxazolinyl)phenylphosphonite)] (1013395-06-6)

Guidance literature:

In tetrahydrofuran; anhyd. CoCl2 (1.1 mmol) was added to a soln. of a ligand (1.1 mmol) in THF; stirring for 3 h at room temp.; THF was removed under reduced pressure; powder was dried overnight undervac.;

DOI:10.1039/b717021c

Reference yield: 94.0%

dichloro bis(acetonitrile) palladium(II) (21264-30-2,90243-59-7,14592-56-4) + sodium tetrakis[(3,5-di-trifluoromethyl)phenyl]borate (79060-88-1) + bis(4,4-dimethyl-2-(1-hydroxy-1-methylethyl)-4,5-dihydrooxazole)phenylphosphonite (286407-90-7) → [Pd(chloride)(PhP(OCMe2(C3H2NOMe2))2)][B(C6H3(CF3)2)4] (1196911-82-6)

Guidance literature:

In dichloromethane; byproducts: NaCl; (inert atm.), Schlenk techniques; dissolving palladium complex in soln. of phosphorus compd. in CH2Cl2, after 1 h addn. of boron compd., stirring overnight at room temp.; filtration, evapn. under reduced pressure, washing with pentane, drying under vacuum, elem. anal.;

DOI:10.1021/ic901579u

upstream raw materials:

4,4'-dimethyl-2-(1-hydroxy-1-methylethyl)-4,5-dihydrooxazole

Dichlorophenylphosphine

Downstream raw materials:

[Pd(C₃H₅)C₆H₅PC₁₆H₂₈N₂O₄]⁽¹⁺⁾*PF₆^(1-)=[Pd(C₃H₅)C₆H₅PC₁₆H₂₈N₂O₄]PF₆

[PdCl(CH₂CHCH₂)(bis(2-oxazoline-4,4-dimethyl-2-hydroxydimethyl)phenylphosphonite)]

Pd(CH₃)ClC₆H₅PC₁₆H₂₈N₂O₄

[Ni(bis(4,4-dimethyl-2-(1-hydroxy-1-methylethyl)-4,5-dihydrooxazole)phenylphosphonite)Cl₂]