2-Methylphenylboronic acid

Base Information

Chemical Name:2-Methylphenylboronic acid
CAS No.:16419-60-6
Molecular Formula:C7H9BO2
Molecular Weight:135.958
Hs Code.:29163990
DSSTox Substance ID:DTXSID40369820
Nikkaji Number:J805.710I
Wikidata:Q72509288
Mol file:16419-60-6.mol

Synonyms:para-tolylboronic acid;tolylboronic acid

Suppliers and Price of 2-Methylphenylboronic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
2-Methylphenylboronic acid
25g
$ 388.00

TRC
2-MethylphenylboronicAcid
10mg
$ 45.00

TCI Chemical
2-Methylphenylboronic Acid (contains varying amounts of Anhydride)
25g
$ 67.00

TCI Chemical
2-Methylphenylboronic Acid (contains varying amounts of Anhydride)
5g
$ 22.00

Synthonix
o-Tolylboronic acid 98%
100g
$ 300.00

Synthonix
o-Tolylboronic acid 98%
25g
$ 110.00

Synthonix
o-Tolylboronic acid 98%
1g
$ 20.00

Synthonix
o-Tolylboronic acid 98%
5g
$ 40.00

SynQuest Laboratories
2-Methylbenzeneboronic acid
500 g
$ 432.00

SynQuest Laboratories
2-Methylbenzeneboronic acid
25 g
$ 29.00

Total 161 raw suppliers

Chemical Property of 2-Methylphenylboronic acid

Chemical Property:

Appearance/Colour:beige crystalline powder
Vapor Pressure:8.13E-05mmHg at 25°C
Melting Point:162-164 °C(lit.)
Refractive Index:1.583
Boiling Point:283.4 °C at 760 mmHg
PKA:8.61±0.58(Predicted)
Flash Point:125.2 °C
PSA：40.46000
Density:1.1 g/cm³
LogP:-0.32520
Storage Temp.:0-6°C
Solubility.:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Water Solubility.:Slightly soluble in water.
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:136.0695597
Heavy Atom Count:10
Complexity:106

Purity/Quality:

99.90% ^*data from raw suppliers

2-Methylphenylboronic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36-37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:B(C1=CC=CC=C1C)(O)O
Description 2-Methylphenylboronic acid is an important organic boronic acid compound, which is widely used in Suzuki cross-coupling reaction and has important application value in the fields of organic synthesis and medicine and chemical industry.
Physical properties beige crystalline powder
Uses suzuki reaction 2-Methylbenzeneboronic acid is a reagent used for Pd-catalyzed arylation using Suzuki-Miyaura cross-coupling in water, Ruthenium catalyzed direct arylation reactions, Ligand-free copper-catalyzed coupling reactions, Rhodium-catalyzed asymmetric 1,4-addition reactions. Reagent used in Preparation of chiral monophosphorus ligands in asymmetric Suzuki-Miyaura coupling reaction, Human farnesyl pyrophosphate synthase inhibitors as antitumor agents for multiple myeloma cells

Technology Process of 2-Methylphenylboronic acid

There total 34 articles about 2-Methylphenylboronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 195062-59-0
2-methylphenylboronic acid pinacol ester

: 16419-60-6
2-Methylphenylboronic acid

Guidance literature:: 2-methylphenylboronic acid pinacol ester; With potassium hydrogen difluoride; In methanol; at 20 ℃; for 0.25h;

With chloro-trimethyl-silane; water; In acetonitrile; for 1h;
DOI:10.1016/j.tetlet.2005.09.101

Reference yield: 97.0%

: 95-49-8
2-methylchlorobenzene

: 605-39-0
2,2'-dimethyl-1,1'-biphenyl

: 16419-60-6
2-Methylphenylboronic acid

Guidance literature:: With cesium fluoride; Pd(dba)2; In toluene;

Reference yield: 92.0%

: 95-46-5
2-methylphenyl bromide

: 16419-60-6
2-Methylphenylboronic acid

Guidance literature:: 2-methylphenyl bromide; With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 0.5h;

With Trimethyl borate; In tetrahydrofuran; at -78 - 20 ℃;
DOI:10.1039/b412932f