phenyl (2,3:5,6-di-O-isopropylidene-α-D-mannofuranosyl) sulfone

Base Information

• Chemical Name: phenyl (2,3:5,6-di-O-isopropylidene-α-D-mannofuranosyl) sulfone
• CAS No.: 99322-64-2
• Molecular Formula: C₁₈H₂₄O₇S
• Molecular Weight: 384.45
• Mol file: 99322-64-2.mol

Synonyms:phenyl (2,3:5,6-di-O-isopropylidene-α-D-mannofuranosyl) sulfone

Chemical Property of phenyl (2,3:5,6-di-O-isopropylidene-α-D-mannofuranosyl) sulfone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of phenyl (2,3:5,6-di-O-isopropylidene-α-D-mannofuranosyl) sulfone

There total 2 articles about phenyl (2,3:5,6-di-O-isopropylidene-α-D-mannofuranosyl) sulfone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

phenyl 2,3;5,6-di-O-isopropylidene-1-thio-β-D-mannofuranoside (67222-87-1) → phenyl (2,3:5,6-di-O-isopropylidene-α-D-mannofuranosyl) sulfone (99322-64-2)

Guidance literature:

With sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 0 - 20 ℃; for 12h;

DOI:10.1055/s-2001-10802

Reference yield: 61.0%

phenyl (2,3:5,6-di-O-isopropylidene-1-nitro-α/β-D-mannofuranosyl) sulfone → phenyl (2,3:5,6-di-O-isopropylidene-α-D-mannofuranosyl) sulfone (99322-64-2)

Guidance literature:

With azobisisobutyronitrile; tri-n-butyl-tin hydride; In toluene; for 4h;

DOI:10.1002/hlca.19850680426

Reference yield: 88.0%

phenyl (2,3:5,6-di-O-isopropylidene-α-D-mannofuranosyl) sulfone (99322-64-2) → (2S,3R)-5-Benzenesulfonyl-2-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2,3-dihydro-furan-3-ol (220458-74-2)

Guidance literature:

With methyllithium lithium bromide; In tetrahydrofuran; at -78 ℃; for 1.33333h;

DOI:10.1055/s-2001-10802

upstream raw materials:

phenyl 2,3;5,6-di-O-isopropylidene-1-thio-β-D-mannofuranoside

Downstream raw materials:

(2S,3R)-5-Benzenesulfonyl-2-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2,3-dihydro-furan-3-ol