2-Amino-2-(4-chlorophenyl)acetic acid

Base Information Edit

Chemical Name:2-Amino-2-(4-chlorophenyl)acetic acid
CAS No.:6212-33-5
Deprecated CAS:7292-70-8
Molecular Formula:C8H8ClNO2
Molecular Weight:185.61
Hs Code.:2922499990
European Community (EC) Number:612-944-6,674-625-8
UNII:RM2JW43TGA
DSSTox Substance ID:DTXSID40863712
Nikkaji Number:J360.089K
ChEMBL ID:CHEMBL133182
Mol file:6212-33-5.mol

Synonyms:6212-33-5;2-amino-2-(4-chlorophenyl)acetic acid;DL-4-Chlorophenylglycine;DL-2-(4-Chlorophenyl)glycine;Amino(4-chlorophenyl)acetic acid;Amino-(4-chloro-phenyl)-acetic acid;4-chlorophenylglycine;DL-(4-Chlorophenyl)glycine;(+/-)-4-Chlorophenylglycine;2-(4-Chlorophenyl)glycine;MFCD00049328;BENZENEACETIC ACID, ALPHA-AMINO-4-CHLORO-;CHEMBL133182;Benzeneacetic acid, .alpha.-amino-4-chloro-;L-4-Chlorophenylglycine;4-chloro-dl-phenylglycine;MFCD03701467;MFCD03839815;h-dl-phg(4-cl)-oh;methylN-carbamoylmaleamate;RM2JW43TGA;2-(p-chlorophenyl)glycine;DL-2-(4-Chlorophenyl );4-Chloro-DL-2-phenylglycine;dl-2-(p-Chlorophenyl)glycine;SCHEMBL390594;(4-Chlorophenyl)glycine, DL-;DTXSID40863712;Amino(4-chlorophenyl)acetic acid #;BCP25773;BBL022163;BDBM50179705;p-chloro-alpha-aminophenylacetic acid;STK130690;AKOS000189147;AKOS016051256;alpha-Amino-4-chlorobenzeneacetic acid;7L-304S;AB02094;AB15770;AB16238;AB88361;Benzeneacetic acid, a-amino-4-chloro-;CS-W002237;HY-W002237;DL-alpha-Amino-4-chlorophenylacetic Acid;SY017756;SY034115;SY034129;AM20060793;BB 0249643;FT-0600927;FT-0625383;FT-0630025;FT-0680568;EN300-88024;(+/-)-4-Chlorophenylglycine, >=98.0% (TLC);Q-102258;F2147-0645;Z317024646;(+/-)-4-CHLOROPHENYLGLYCINE 4-CHLOROPHENYL GLYCINE AMINO-(4-CHLORO-PHENYL)-ACETIC ACID (+/-)-ALPHA-AMINO-4-CHLOROPHENYLACETIC ACID

Suppliers and Price of 2-Amino-2-(4-chlorophenyl)acetic acid

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
DL-4-Chlorophenylglycine
500mg
$ 50.00

TRC
DL-4-Chlorophenylglycine
5g
$ 85.00

TCI Chemical
DL-2-(4-Chlorophenyl)glycine >98.0%(T)
5g
$ 26.00

TCI Chemical
DL-2-(4-Chlorophenyl)glycine >98.0%(T)
1g
$ 14.00

TCI Chemical
DL-2-(4-Chlorophenyl)glycine >98.0%(T)
25g
$ 83.00

Sigma-Aldrich
(±)-4-Chlorophenylglycine ≥98.0% (TLC)
100g-f
$ 346.00

Sigma-Aldrich
(±)-4-Chlorophenylglycine ≥98.0%(TLC)
25 g
$ 72.00

Sigma-Aldrich
(±)-4-Chlorophenylglycine ≥98.0% (TLC)
25g-f
$ 109.00

Matrix Scientific
2-Amino-2-(4-chlorophenyl)acetic acid >95%
25g
$ 111.00

Matrix Scientific
2-Amino-2-(4-chlorophenyl)acetic acid >95%
5g
$ 36.00

Total 115 raw suppliers

Chemical Property of 2-Amino-2-(4-chlorophenyl)acetic acid Edit

Chemical Property:

Appearance/Colour:white to light yellow crystal powder
Vapor Pressure:7.45E-05mmHg at 25°C
Melting Point:220-230 °C
Refractive Index:1.603
Boiling Point:328.8 °C at 760 mmHg
PKA:1.81±0.10(Predicted)
Flash Point:152.7 °C
PSA：63.32000
Density:1.392 g/cm³
LogP:2.12470
Storage Temp.:Keep in dark place,Inert atmosphere,Room temperature
Solubility.:Soluble in 0.1mol/L NaOH (almost transparency).
XLogP3:-1.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:185.0243562
Heavy Atom Count:12
Complexity:166

Purity/Quality:

99% ^*data from raw suppliers

DL-4-Chlorophenylglycine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22-36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C(C(=O)O)N)Cl
Uses It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff.

Technology Process of 2-Amino-2-(4-chlorophenyl)acetic acid

There total 18 articles about 2-Amino-2-(4-chlorophenyl)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 7099-88-9
4-chlorophenylglyoxylic acid

: 6212-33-5,7292-70-8
2-(4-Chlorophenyl)glycine

Guidance literature:: With 4-methoxy-N-(1-(naphthalen-2-yl)ethylidene)aniline; ammonium formate; In methanol; at 80 ℃; for 12h; chemoselective reaction; Inert atmosphere;
DOI:10.1002/chem.201303541

Reference yield: 91.0%

: 6212-33-5,7292-70-8
2-(4-Chlorophenyl)glycine

Guidance literature:: With ammonium formate; In methanol; at 80 ℃; for 0.166667h; Inert atmosphere;

With formic acid; C₂₉H₃₂ClIrNO; triethylamine; In methanol; at 80 ℃;