E-(2R,3R)-3-O-(benzyloxymethylene)-1,2-O-isopropylidene-5-octene-4,7-dione-1,2,3-triol, 7-dimethyl ketal

Base Information

Chemical Name:E-(2R,3R)-3-O-(benzyloxymethylene)-1,2-O-isopropylidene-5-octene-4,7-dione-1,2,3-triol, 7-dimethyl ketal
CAS No.:107941-12-8
Molecular Formula:C₂₁H₃₀O₇
Molecular Weight:394.465
Hs Code.:

Synonyms:E-(2R,3R)-3-O-(benzyloxymethylene)-1,2-O-isopropylidene-5-octene-4,7-dione-1,2,3-triol, 7-dimethyl ketal

Suppliers and Price of E-(2R,3R)-3-O-(benzyloxymethylene)-1,2-O-isopropylidene-5-octene-4,7-dione-1,2,3-triol, 7-dimethyl ketal

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of E-(2R,3R)-3-O-(benzyloxymethylene)-1,2-O-isopropylidene-5-octene-4,7-dione-1,2,3-triol, 7-dimethyl ketal

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of E-(2R,3R)-3-O-(benzyloxymethylene)-1,2-O-isopropylidene-5-octene-4,7-dione-1,2,3-triol, 7-dimethyl ketal

There total 7 articles about E-(2R,3R)-3-O-(benzyloxymethylene)-1,2-O-isopropylidene-5-octene-4,7-dione-1,2,3-triol, 7-dimethyl ketal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 1445-45-0
Trimethyl orthoacetate

: 107959-94-4
E-(2R,3R)-3-O-(benzyloxymethylene)-1,2-O-isopropylidene-5-octene-4,7-dione-1,2,3-triol

: 107941-12-8
E-(2R,3R)-3-O-(benzyloxymethylene)-1,2-O-isopropylidene-5-octene-4,7-dione-1,2,3-triol, 7-dimethyl ketal

Guidance literature:: camphor-10-sulfonic acid; In methanol; at 0 ℃; for 6h;
DOI:10.1016/S0040-4039(00)84354-3

Reference yield:

: 3587-60-8
Benzyloxymethyl chloride

: 107941-12-8
E-(2R,3R)-3-O-(benzyloxymethylene)-1,2-O-isopropylidene-5-octene-4,7-dione-1,2,3-triol, 7-dimethyl ketal

Guidance literature:: Multi-step reaction with 3 steps

1: 90 percent / diisopropylethylamine / CH₂Cl₂ / 24 h / Ambient temperature

2: 80 percent / pyridine, bromine / acetonitrile; H₂O / 1.) -20 deg C 2.) rt, 2 h

3: 92 percent / camphorsulfonic acid / methanol / 0 °C

With pyridine; camphor-10-sulfonic acid; bromine; N-ethyl-N,N-diisopropylamine; In methanol; dichloromethane; water; acetonitrile;
DOI:10.1021/ja00247a025

Reference yield:

: 103061-82-1
(2R,3R)-1,2-O-isopropylidene-3-<2-(5-methylfuryl)>-1,2,3-propanetriol

: 107941-12-8
E-(2R,3R)-3-O-(benzyloxymethylene)-1,2-O-isopropylidene-5-octene-4,7-dione-1,2,3-triol, 7-dimethyl ketal

Guidance literature:: Multi-step reaction with 3 steps

1: 90 percent / diisopropylethylamine / CH₂Cl₂ / 24 h / Ambient temperature

2: 80 percent / pyridine, bromine / acetonitrile; H₂O / 1.) -20 deg C 2.) rt, 2 h

3: 92 percent / camphorsulfonic acid / methanol / 0 °C

With pyridine; camphor-10-sulfonic acid; bromine; N-ethyl-N,N-diisopropylamine; In methanol; dichloromethane; water; acetonitrile;
DOI:10.1021/ja00247a025