[(1R,2S,3R,4R,5S)-5-Benzyloxycarbonylamino-4-((2S,3R,4R,5S,6R)-3-benzyloxycarbonylamino-4,5-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-2,3-dihydroxy-cyclohexyl]-carbamic acid benzyl ester

Base Information

Chemical Name:[(1R,2S,3R,4R,5S)-5-Benzyloxycarbonylamino-4-((2S,3R,4R,5S,6R)-3-benzyloxycarbonylamino-4,5-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-2,3-dihydroxy-cyclohexyl]-carbamic acid benzyl ester
CAS No.:23600-10-4
Molecular Formula:C₃₆H₄₃N₃O₁₃
Molecular Weight:725.75
Hs Code.:

[(1R,2S,3R,4R,5S)-5-Benzyloxycarbonylamino-4-((2S,3R,4R,5S,6R)-3-benzyloxycarbonylamino-4,5-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-2,3-dihydroxy-cyclohexyl]-carbamic acid benzyl ester

Synonyms:[(1R,2S,3R,4R,5S)-5-Benzyloxycarbonylamino-4-((2S,3R,4R,5S,6R)-3-benzyloxycarbonylamino-4,5-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-2,3-dihydroxy-cyclohexyl]-carbamic acid benzyl ester

Suppliers and Price of [(1R,2S,3R,4R,5S)-5-Benzyloxycarbonylamino-4-((2S,3R,4R,5S,6R)-3-benzyloxycarbonylamino-4,5-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-2,3-dihydroxy-cyclohexyl]-carbamic acid benzyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of [(1R,2S,3R,4R,5S)-5-Benzyloxycarbonylamino-4-((2S,3R,4R,5S,6R)-3-benzyloxycarbonylamino-4,5-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-2,3-dihydroxy-cyclohexyl]-carbamic acid benzyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of [(1R,2S,3R,4R,5S)-5-Benzyloxycarbonylamino-4-((2S,3R,4R,5S,6R)-3-benzyloxycarbonylamino-4,5-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-2,3-dihydroxy-cyclohexyl]-carbamic acid benzyl ester

There total 7 articles about [(1R,2S,3R,4R,5S)-5-Benzyloxycarbonylamino-4-((2S,3R,4R,5S,6R)-3-benzyloxycarbonylamino-4,5-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-2,3-dihydroxy-cyclohexyl]-carbamic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 18685-97-7,68422-90-2,74081-52-0
paromamine trihydrochloride

: 501-53-1,94274-21-2
benzyl chloroformate

: 23600-10-4
[(1R,2S,3R,4R,5S)-5-Benzyloxycarbonylamino-4-((2S,3R,4R,5S,6R)-3-benzyloxycarbonylamino-4,5-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-2,3-dihydroxy-cyclohexyl]-carbamic acid benzyl ester

Guidance literature:: With sodium carbonate; In water; acetone; toluene; at 5 - 20 ℃; for 4h;
DOI:10.1002/anie.201204083

Reference yield:

: 933-40-4
cycloxexanone dimethyl ketal

: 23600-10-4
[(1R,2S,3R,4R,5S)-5-Benzyloxycarbonylamino-4-((2S,3R,4R,5S,6R)-3-benzyloxycarbonylamino-4,5-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-2,3-dihydroxy-cyclohexyl]-carbamic acid benzyl ester

Guidance literature:: Multi-step reaction with 6 steps

1: p-TsOH_.H₂O / dimethylformamide / 2.5 h / 80 °C

2: AcONa / 30 h / Ambient temperature

3: 89 percent / NaBH₄, 95percent EtOH / 3.5 h / Ambient temperature

4: HClO₄ / acetone / 0.17 h / Ambient temperature

5: H₂ / Raney Ni T-4 / acetic acid; ethanol

6: 5percent aq. Na₂CO₃ / acetone

With sodium tetrahydroborate; perchloric acid; ethanol; hydrogen; sodium acetate; sodium carbonate; toluene-4-sulfonic acid; Raney Ni T-4; In ethanol; acetic acid; N,N-dimethyl-formamide; acetone;
DOI:10.1016/S0040-4039(00)85695-6

Reference yield:

: [(2S,3R,4R,5S,6R)-2-((1R,2R,3S,4R,6S)-6-Benzyloxycarbonylamino-2,3-dihydroxy-4-nitro-cyclohexyloxy)-4,5-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-3-yl]-carbamic acid benzyl ester

: 23600-10-4
[(1R,2S,3R,4R,5S)-5-Benzyloxycarbonylamino-4-((2S,3R,4R,5S,6R)-3-benzyloxycarbonylamino-4,5-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-2,3-dihydroxy-cyclohexyl]-carbamic acid benzyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: H₂ / Raney Ni T-4 / acetic acid; ethanol

2: 5percent aq. Na₂CO₃ / acetone

With hydrogen; sodium carbonate; Raney Ni T-4; In ethanol; acetic acid; acetone;
DOI:10.1016/S0040-4039(00)85695-6