1,1-Dimethoxycyclohexane

Base Information

• Chemical Name: 1,1-Dimethoxycyclohexane
• CAS No.: 933-40-4
• Molecular Formula: C8H16O2
• Molecular Weight: 144.214
• Hs Code.: 2911000000
• European Community (EC) Number: 629-653-5
• DSSTox Substance ID: DTXSID00239373
• Nikkaji Number: J119.632D
• Wikidata: Q72467857
• Mol file: 933-40-4.mol

Synonyms:1,1-DIMETHOXYCYCLOHEXANE;933-40-4;Cyclohexanone dimethyl ketal;Cyclohexane, 1,1-dimethoxy-;Cyclohexanone, dimethyl acetal;Cyclohexanone Dimethylketal;dimethoxycyclohexane;1,1-dimethoxy-cyclohexane;cyclohexanone dimethyl acetal;cyclohexanone-dimethylacetal;SCHEMBL201561;DTXSID00239373;Cyclohexanone dimethyl ketal, 99%;MFCD00043714;AKOS015851762;BS-22409;CS-0179761;D1372;FT-0624196;InChI=1/C8H16O2/c1-9-8(10-2)6-4-3-5-7-8/h3-7H2,1-2H

Chemical Property of 1,1-Dimethoxycyclohexane

Chemical Property:

• Appearance/Colour: COLORLESS LIQUID
• Vapor Pressure: 2.84mmHg at 25°C
• Refractive Index: n20/D 1.439(lit.)
• Boiling Point: 162.3 °C at 760 mmHg
• Flash Point: 40.6 °C
• PSA: 18.46000
• Density: 0.92 g/cm³
• LogP: 1.93960
• XLogP3: 1.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 144.115029749
• Heavy Atom Count: 10
• Complexity: 89.4

Purity/Quality:

98%,99%, ^*data from raw suppliers

1,1-Dimethoxycyclohexane ^*data from reagent suppliers

Safty Information:

• Statements: 10-18
• Safety Statements: 16-51

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: COC1(CCCCC1)OC

Technology Process of 1,1-Dimethoxycyclohexane

There total 45 articles about 1,1-Dimethoxycyclohexane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methanol (67-56-1) + cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) + trimethyl orthoformate (149-73-5) → cycloxexanone dimethyl ketal (933-40-4)

Guidance literature:

With povidone-iodine; at 30 ℃; for 6h; Green chemistry;

DOI:10.1016/j.tet.2021.132250

Reference yield: 100.0%

methanol (67-56-1) + cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) → cycloxexanone dimethyl ketal (933-40-4)

Guidance literature:

With trimethyl orthoformate; at 40 ℃; for 8h; under 6000480 Torr;

DOI:10.1055/s-2005-872229

Reference yield: 99.0%

cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) + trimethyl orthoformate (149-73-5) → cycloxexanone dimethyl ketal (933-40-4)

Guidance literature:

With tetra-N-butylammonium tribromide; In methanol; at 20 ℃; for 0.33h;

DOI:10.1021/jo025701o

upstream raw materials:

methanol

cyclohexanone

tetramethylorthosilicate

dimethylsulfite

Downstream raw materials:

1,3,6',3-tetrakis(N-benzyloxycarbonyl)-4,6-O-cyclohexylidenekanamycin A

5-(1-Methoxy-cyclohexyl)-5H-furan-2-one

2-cyclohexylanisole

4-cyclohexylanisole

Refernces

• 1、 Iwamoto, Masakazu,Tanaka, Yasuhiro,Sawamura, Naoki,Namba, Seitaro. "Remarkable Effect of Pore Size on the Catalytic Activity of Mesoporous Silica for the Acetalization of Cyclohexanone with Methanol". . p. 13032 - 13033. Retrieved 2003.
• 2、 Tudesco, Michael T.,Moschetta, Eric G.,Voight, Eric A.. "Scale-Up of a Continuous Extraction Process for Driving an Equilibrium-Limited Reaction to Completion". . p. 1564 - 1569. Retrieved 2018.
• 3、 Jiang, Jinlong,Wu, Mei,Yang, Yong,Duanmu, Chuansong,Chen, Jing,Gu, Xu. "Synthesis and catalytic performance of ZSM-5/MCM-41 composite molecular sieve from palygorskite". . p. 1883 - 1889. Retrieved 2017.
• 4、 He, Junkai,Kankanam Kapuge, Tharindu,Kerns, Peter,Meguerdichian, Andrew G.,Suib, Steven L.,Thalgaspitiya, Wimalika R. K.. "A novel, mesoporous molybdenum doped titanium dioxide/reduced graphene oxide composite as a green, highly efficient solid acid catalyst for acetalization". . p. 3786 - 3795. Retrieved 2020/04/03.