benzyl 4-(4-(4-fluoro-3-(trifluoromethyl)phenyl)-1H-imidazol-2-yl)piperidine-1-carboxylate

Base Information

Chemical Name:benzyl 4-(4-(4-fluoro-3-(trifluoromethyl)phenyl)-1H-imidazol-2-yl)piperidine-1-carboxylate
CAS No.:1428252-98-5
Molecular Formula:C₂₃H₂₁F₄N₃O₂
Molecular Weight:447.432
Hs Code.:

Synonyms:benzyl 4-(4-(4-fluoro-3-(trifluoromethyl)phenyl)-1H-imidazol-2-yl)piperidine-1-carboxylate

Suppliers and Price of benzyl 4-(4-(4-fluoro-3-(trifluoromethyl)phenyl)-1H-imidazol-2-yl)piperidine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of benzyl 4-(4-(4-fluoro-3-(trifluoromethyl)phenyl)-1H-imidazol-2-yl)piperidine-1-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of benzyl 4-(4-(4-fluoro-3-(trifluoromethyl)phenyl)-1H-imidazol-2-yl)piperidine-1-carboxylate

There total 1 articles about benzyl 4-(4-(4-fluoro-3-(trifluoromethyl)phenyl)-1H-imidazol-2-yl)piperidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 13139-17-8
N-(Benzyloxycarbonyloxy)succinimide

: 4-(4-(4-fluoro-3-(trifluoromethyl)phenyl)-1H-imidazol-2-yl)piperidine hydrochloride

: 1428252-98-5
benzyl 4-(4-(4-fluoro-3-(trifluoromethyl)phenyl)-1H-imidazol-2-yl)piperidine-1-carboxylate

Guidance literature:: 4-(4-(4-fluoro-3-(trifluoromethyl)phenyl)-1H-imidazol-2-yl)piperidine hydrochloride; With N-ethyl-N,N-diisopropylamine; In dichloromethane; for 0.0833333h;

N-(Benzyloxycarbonyloxy)succinimide; In dichloromethane; at 20 ℃;

Reference yield: 76.2%

: 4360-63-8
2-bromomethyl-1,3-dioxolane

: 1428252-98-5
benzyl 4-(4-(4-fluoro-3-(trifluoromethyl)phenyl)-1H-imidazol-2-yl)piperidine-1-carboxylate

: 1428252-99-6
benzyl 4-(1-((1,3-dioxolan-2-yl)methyl)-4-(4-fluoro-3-(trifluoromethyl)phenyl)-1H-imidazol-2-yl)piperidine-1-carboxylate

Guidance literature:: benzyl 4-(4-(4-fluoro-3-(trifluoromethyl)phenyl)-1H-imidazol-2-yl)piperidine-1-carboxylate; With sodium hexamethyldisilazane; In tetrahydrofuran; at -20 - 20 ℃; for 0.5h;

2-bromomethyl-1,3-dioxolane; In tetrahydrofuran; at 20 ℃; for 0.0833333h;

In tetrahydrofuran; dimethyl sulfoxide; at 100 ℃; for 2h; Microwave irradiation;

Reference yield: 16.0%

: 1428252-98-5
benzyl 4-(4-(4-fluoro-3-(trifluoromethyl)phenyl)-1H-imidazol-2-yl)piperidine-1-carboxylate

: 141699-57-2
3-methanesulfonyloxy-pyrrolidine-1-carboxylic acid tert-butyl ester

: 1428253-06-8
benzyl 4-(1-(1-(tert-butoxycarbonyl)pyrrolidin-3-yl)-4-(4-fluoro-3-(trifluoromethyl)phenyl)-1H-imidazol-2-yl)piperidine-1-carboxylate

Guidance literature:: benzyl 4-(4-(4-fluoro-3-(trifluoromethyl)phenyl)-1H-imidazol-2-yl)piperidine-1-carboxylate; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 20 ℃; for 0.333333h;

3-methanesulfonyloxy-pyrrolidine-1-carboxylic acid tert-butyl ester; In N,N-dimethyl-formamide; mineral oil; at 85 ℃; for 5h;