5-chloro-4-iodo-N-[2-(methyloxy)-4-(4-morpholinyl)phenyl]-2-pyridinamine

Base Information

Chemical Name:5-chloro-4-iodo-N-[2-(methyloxy)-4-(4-morpholinyl)phenyl]-2-pyridinamine
CAS No.:1184931-51-8
Molecular Formula:C₁₆H₁₇ClIN₃O₂
Molecular Weight:445.687
Hs Code.:

Synonyms:5-chloro-4-iodo-N-[2-(methyloxy)-4-(4-morpholinyl)phenyl]-2-pyridinamine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-chloro-4-iodo-N-[2-(methyloxy)-4-(4-morpholinyl)phenyl]-2-pyridinamine

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Technology Process of 5-chloro-4-iodo-N-[2-(methyloxy)-4-(4-morpholinyl)phenyl]-2-pyridinamine

There total 1 articles about 5-chloro-4-iodo-N-[2-(methyloxy)-4-(4-morpholinyl)phenyl]-2-pyridinamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 18.0%

: 209960-91-8
2-methoxy-4-morpholinoaniline

: 659731-48-3
5-chloro-2-fluoro-4-iodopyridine

: 1184931-51-8
5-chloro-4-iodo-N-[2-(methyloxy)-4-(4-morpholinyl)phenyl]-2-pyridinamine

Guidance literature:: 2-methoxy-4-morpholinoaniline; 5-chloro-2-fluoro-4-iodopyridine; With hydrogenchloride; In 1,4-dioxane; water; at 85 ℃; for 36h; vessel sealed;

With sodium hydrogencarbonate; In 1,4-dioxane; water; ethyl acetate;

Reference yield: 57.0%

: 1184931-51-8
5-chloro-4-iodo-N-[2-(methyloxy)-4-(4-morpholinyl)phenyl]-2-pyridinamine

: 4141-08-6
2-Amino-N-methylbenzamid

: 2-[(5-chloro-2-{[2-(methyloxy)-(4-morpholinyl)phenyl]amino}-4-pyridinyl)amino]-N-methylbenzamide

Guidance literature:: With caesium carbonate; palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; In 1,4-dioxane; at 180 ℃; for 0.333333h; microwave irradiation; Inert atmosphere;