6-Chloro-3-methyluracil

Base Information

Chemical Name:6-Chloro-3-methyluracil
CAS No.:4318-56-3
Molecular Formula:C5H5ClN2O2
Molecular Weight:160.56
Hs Code.:29335990
European Community (EC) Number:610-113-2
NSC Number:55976
UNII:AYQ4JL346J
DSSTox Substance ID:DTXSID00195763
Nikkaji Number:J348.053D
Wikidata:Q72455547
ChEMBL ID:CHEMBL1556752
Mol file:4318-56-3.mol

Synonyms:6-Chloro-3-methyluracil;4318-56-3;6-chloro-3-methylpyrimidine-2,4(1H,3H)-dione;3-Methyl-6-chlorouracil;6-chloro-3-methyl-1H-pyrimidine-2,4-dione;2,4(1H,3H)-Pyrimidinedione, 6-chloro-3-methyl-;6-CHLORO-2-HYDROXY-3-METHYL-3,4-DIHYDROPYRIMIDIN-4-ONE;AYQ4JL346J;6-chloro-3-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione;6-Chloro-3-methyl-2,4(1H,3H)-pyrimidinedione;MFCD01074837;NSC 55976;NSC-55976;6-Chloro-3-methylpyrimidine-2,4[1H,3H]-dione;3-Methyl-6-chlorouraci;NSC55976;6-Chloro-3-methyl uracil;UNII-AYQ4JL346J;MLS000723901;SCHEMBL220198;Uracil, 6-chloro-3-methyl-;CHEMBL1556752;SCHEMBL21653786;DTXSID00195763;CHEBI:189258;HMS2629J15;BCP27871;6-Chloro-3-methyluracil, >=98%;GEO-00748;STK177274;AKOS000264936;AC-8826;CS-W020095;MS-1869;SB37175;NCGC00245854-01;SMR000305496;SY002003;AM20100138;C2300;FT-0621044;EN300-189212;F11245;6-chloro-2-hydroxy-3-methylpyrimidin-4(3H)-one;AB-323/25048121;6-Chloro-3-methyl-2,4(1H,3H)-pyrimidinedione #;W-202755;F8885-4682

Suppliers and Price of 6-Chloro-3-methyluracil

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
6-Chloro-3-methyluracil
10g
$ 403.00

TRC
6-Chloro-3-methyluracil
10g
$ 120.00

TCI Chemical
6-Chloro-3-methyluracil >98.0%(HPLC)(T)
25g
$ 134.00

TCI Chemical
6-Chloro-3-methyluracil >98.0%(HPLC)(T)
5g
$ 44.00

SynQuest Laboratories
6-Chloro-3-methyluracil
1 g
$ 26.00

SynQuest Laboratories
6-Chloro-3-methyluracil
25 g
$ 120.00

SynQuest Laboratories
6-Chloro-3-methyluracil
5 g
$ 96.00

Sigma-Aldrich
6-Chloro-3-methyluracil ≥98%
100g
$ 151.00

Matrix Scientific
6-Chloro-3-methyluracil 97%
100g
$ 92.00

Matrix Scientific
6-Chloro-3-methyluracil 97%
25g
$ 43.00

Total 206 raw suppliers

Chemical Property of 6-Chloro-3-methyluracil

Chemical Property:

Vapor Pressure:0.00101mmHg at 25°C
Melting Point:278-280°C (dec.)
Refractive Index:1.58
Boiling Point:268.7 °C at 760 mmHg
PKA:7.16±0.40(Predicted)
Flash Point:116.3 °C
PSA：54.86000
Density:1.51 g/cm³
LogP:-0.27300
Storage Temp.:Keep in dark place,Sealed in dry,Room Temperature
XLogP3:0
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:160.0039551
Heavy Atom Count:10
Complexity:224

Purity/Quality:

99% up ^*data from raw suppliers

6-Chloro-3-methyluracil ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C(=O)C=C(NC1=O)Cl
Uses 6-Chloro-3-methyluracil have been used in the synthesis of antibacterial agents as inhibitors of Helicobacter pylori glutamate racemase.

Technology Process of 6-Chloro-3-methyluracil

There total 8 articles about 6-Chloro-3-methyluracil which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.3%

: 1-methyl-2,4,6(1H,3H,5H)-pyrimidinetrione sodium salt

: 4318-56-3
3-methyl-6-chlorouracil

Guidance literature:: With trichlorophosphate; In water; acetonitrile; at 8 - 80 ℃; for 2h; Temperature;

Reference yield: 81.0%

: 2565-47-1
1-methyl-2,4,6-pyrimidinetrione

: 4318-56-3
3-methyl-6-chlorouracil

Guidance literature:: With water; trichlorophosphate; at 80 ℃; for 4h;
DOI:10.1002/jhet.1111

Reference yield: 80.0%

: 882872-13-1
6-hydroxy-3-methylpyrimidine-2,4(1H,3H)-dione

: 4318-56-3
3-methyl-6-chlorouracil

Guidance literature:: With trichlorophosphate; In acetonitrile; at 120 ℃; for 0.333333h; Microwave irradiation;
DOI:10.1016/j.tetlet.2010.09.044